Upadacitinib Impurity 137 CAS CATO-C4X-2405137
| CAS No. | CATO-C4X-2405137 |
| Molecular Formula | C26H31N5O2 |
| Molecular Weight | 445.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Upadacitinib Impurity 137.
CATO supplies Upadacitinib Impurity 137 (CAS CATO-C4X-2405137), a pharmacopoeial impurity reference standard (molecular formula C26H31N5O2, MW 445.56 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C26H31N5O2, Upadacitinib Impurity 137 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 445.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Upadacitinib Impurity 137 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H31N5O2 |
| Molecular Weight | 445.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Upadacitinib Standards
- Upadacitinib Impurity 99 (CAS CATO-C4X-240599)
- Upadacitinib Impurity 171 (CAS CATO-C4X-2405171)
- Upadacitinib Impurity 132 (CAS CATO-C4X-2405132)
- Upadacitinib Impurity 85 (CAS CATO-C4X-240585)
- Upadacitinib Impurity 121 (CAS CATO-C4X-2405121)
- Upadacitinib Impurity 180 (CAS CATO-C4X-2405180)
- Upadacitinib Impurity 63 (CAS CATO-C4X-240563)
- Upadacitinib Impurity 127 (CAS CATO-C4X-2405127)
Recommended Standards
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- SM7280A Impurity 3 (CAS CATO-C4X-32963)
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- Palbociclib Impurity 202 (CAS CATO-C4X-1125202)
- Finasteride Impurity 40 (CAS CATO-C4X-164540)
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- Nimodipine for peak identification CRS (CAS 14255-61-9)
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- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
Why CATO?
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