Upadacitinib Impurity 159 CAS CATO-C4X-2405159
| CAS No. | CATO-C4X-2405159 |
| Molecular Formula | C9H17NO2 |
| Molecular Weight | 171.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Upadacitinib Impurity 159.
As a process- or degradation-related impurity, Upadacitinib Impurity 159 (CAS CATO-C4X-2405159, C9H17NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Upadacitinib Impurity 159 (C9H17NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H17NO2 |
| Molecular Weight | 171.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| Nitrogen Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 142 (CAS CATO-C4X-2405142)
- Upadacitinib Impurity 151 (CAS CATO-C4X-2405151)
- Upadacitinib Impurity 164 (CAS CATO-C4X-2405164)
- Upadacitinib Impurity 202 (CAS CATO-C4X-2405202)
- Upadacitinib Impurity 89 (CAS CATO-C4X-240589)
- Upadacitinib Impurity 174 (CAS CATO-C4X-2405174)
- Upadacitinib Impurity 167 (CAS CATO-C4X-2405167)
- Upadacitinib Impurity 53 (CAS 1046861-47-5)
Recommended Standards
- Ruxolitinib Impurity 87 (CAS CATO-C4X-205887)
- Gabapentin (CAS 60142-96-3)
- (S)-Rasagiline (CAS 185517-74-2)
- Methyl-(Naphthalen-2-Ylmethyl)Azanium (CAS 76532-33-7)
- Urapidil Impurity 104 (CAS CATO-C4X-1924104)
- Vonoprazan Impurity 257 (CAS CATO-C4X-1020257)
- Amlodipine Impurity 101 (CAS 3079028-35-3)
- Preangiotensinogen (11-14) (human) (H-4665.0005) (CAS 102813-98-9)
- 2-Chloro-5-[(3,5-dimethylpiperidin-1-yl)sulfonyl]benzoic acid (CAS 24358-29-0)
- 6-Bromo-4-formylpicolinonitrile (CAS 1289035-24-0)
- 2-{[5-cyano-4-(trifluoromethyl)-[2,3'-bipyridine]-6-yl]sulfanyl}-N-{3-cyano-4H,5H,6H-cyclopenta[b]thiophen-2-yl}acetamide (CAS 625377-03-9)
- Indium(III) nitrate hydrate (99.999%-In) PURATREM (CAS 13465-14-0)
- (2R,3R)-2-(Hydroxymethyl)tetrahydrofuran-3-yl methanesulfonate (CAS 2795130-26-4)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com