Upadacitinib Impurity 158 CAS CATO-C4X-2405158
| CAS No. | CATO-C4X-2405158 |
| Molecular Formula | C15H19NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Upadacitinib Impurity 158 (C15H19NO4C8H11N) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Upadacitinib Impurity 158 (CAS CATO-C4X-2405158) is a certified pharmaceutical impurity reference standard with the molecular formula C15H19NO4C8H11N and a molecular weight of 398.50 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Upadacitinib Impurity 158 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H19NO4 C8H11N |
| Molecular Weight | 398.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Upadacitinib Standards
- Upadacitinib Impurity 53 (CAS 1046861-47-5)
- Upadacitinib Impurity 218 (CAS 117718-83-9)
- Upadacitinib Impurity 17 (CAS 1201186-54-0)
- Upadacitinib Impurity 15 (CAS 1201187-44-1)
- Upadacitinib Impurity 2 (CAS 1201187-46-3)
- Upadacitinib Impurity 28 (CAS 1310726-59-0)
- Upadacitinib (CAS 1310726-60-3)
- Upadacitinib Impurity 18 (CAS 1428243-24-6)
Recommended Standards
- Lomefloxacin Impurity 22 Trifluoroacetate (CAS CATO-C4X-207322)
- Esomeprazole Impurity 23 (CAS 1422063-97-5)
- Aprepitant Impurity 15 (CAS CATO-C4X-116815)
- 1-(3-Ethoxy-4,5-difluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1443327-55-6)
- Methyl 3-{2-[4-(tert-butoxycarbonyl)piperazin-1-yl]ethoxy}thiophene-2-carboxylate (CAS 1215799-66-8)
- 1-(azetidin-3-yl)ethan-1-ol, trifluoroacetic acid (CAS 1955557-74-0)
- 3-(Difluoromethoxy)pyrrolidine hydrochloride (CAS 1638772-00-5)
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- 7-Methyl-1H-pyrrolo[3,2-c]pyridine-3-carbonitrile (CAS 1260383-70-7)
- SAMS Peptide (CAS 125911-68-4)
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