Upadacitinib Impurity 30 CAS CATO-C4X-240530
| CAS No. | CATO-C4X-240530 |
| Molecular Formula | C16H20BrNO3 |
| Molecular Weight | 354.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Upadacitinib Impurity 30 (CAS CATO-C4X-240530, C16H20BrNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Upadacitinib Impurity 30 (C16H20BrNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Upadacitinib Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H20BrNO3 |
| Molecular Weight | 354.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 16 (CAS 1428243-26-8)
- Upadacitinib Impurity 161 (CAS CATO-C4X-2405161)
- Upadacitinib Impurity 29 (CAS 2868258-96-0)
- Upadacitinib Impurity 31 (CAS CATO-C4X-240531)
- Upadacitinib Impurity 87 (and enantiomer) (CAS CATO-C4X-240587)
- Upadacitinib Impurity 33 (CAS 2650489-66-8)
- Upadacitinib Impurity 17 (CAS 1201186-54-0)
- Upadacitinib Impurity 185 (CAS CATO-C4X-2405185)
Recommended Standards
- 3-Phenyl-1-(tetrahydro-2H-pyran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1028092-65-0)
- tert-Butyl 3-(5-bromopyridin-2-yl)-3,6-diazabicyclo[3.1.1]heptane-6-carboxylate (CAS 2222757-10-8)
- 7-(tert-Butyl)-2,4-bis(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (CAS 1186404-55-6)
- Tert-butyl 2-(3-bromobenzyl)-3-oxopyrrolidine-1-carboxylate (CAS 2274804-31-6)
- Pregabalin Impurity PD0310887 (CAS CATO-C4X-131210)
- 2-Chloro-1-(3-chloro-4-hydroxyphenyl)ethan-1-one (CAS 39066-18-7)
- Metaraminol Impurity 78 (CAS 65133-68-8)
- 4-Iodo-N-(1-methyl-1H-indazol-3-yl)benzenesulfonamide (CAS 2085690-77-1)
- (1-Cyclohexylpiperidin-4-yl)methanamine (CAS 132740-53-5)
- 3-Cyclohexyl-1-ethylpyrrolidine-2,5-dione (CAS 588672-39-3)
- Methyl 4-Cyclopropyl-3-methyl-2-oxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate (CAS 2201816-81-9)
- 2,2-Dimethyl-3-oxopentanedinitrile (CAS 1012879-83-2)
- 5-Iodoacetamidoerythrosin (>90%) (CAS 86583-16-6)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
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