Lifitegrast Impurity 134 CAS CATO-C4X-2409134
| CAS No. | CATO-C4X-2409134 |
| Molecular Formula | C27H25Cl2N3O6S |
| Molecular Weight | 590.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Lifitegrast Impurity 134 (C27H25Cl2N3O6S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Lifitegrast Impurity 134 (CAS CATO-C4X-2409134, C27H25Cl2N3O6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lifitegrast Impurity 134 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H25Cl2N3O6S |
| Molecular Weight | 590.47 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 147 (CAS CATO-C4X-2409147)
- Lifitegrast Impurity 89 (CAS CATO-C4X-240989)
- Lifitegrast Impurity 119 (CAS CATO-C4X-2409119)
- Lifitegrast Impurity 16 (CAS 2322380-18-5)
- Lifitegrast Impurity 17 (CAS 2322380-15-2)
- Lifitegrast Impurity 50 (CAS 2762168-17-0)
- Lifitegrast Impurity 160 (CAS CATO-C4X-2409160)
- Lifitegrast Impurity 31 (CAS CATO-C4X-240931)
Recommended Standards
- 1564286-55-0 (3S)-3-(3-Bromo-5-(tert-butyl)phenyl)-3-(2-(3-hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino)benzamido)acetamido)propanoic acid MFCD28385850 Cwhm12 (CAS 1564286-55-0)
- (11bR)-4-Hydroxy-2,6-bis(4-nitrophenyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-oxide (CAS 695162-89-1)
- N,N-Diphenyl-2-(tributylstannyl)benzo[b]thiophen-6-amine (CAS 2416371-35-0)
- (11bS)-4-Hydroxy-2,6-bis(4-nitrophenyl)dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepine 4-Oxide (CAS 878111-16-1)
- Galanthamine Impurity 36 (CAS CATO-C4X-143536)
- Mianserin Impurity 119 (CAS CATO-C4X-1369119)
- Dabigatran Impurity 60 (CAS CATO-C4X-108960)
- Dimethyl 2,2'-(benzylazanediyl)diacetate (CAS 6175-26-4)
- Licochalcone E (CAS 864232-34-8)
- N-(3-(2-Formamidophenyl)-3-oxopropyl)acetamide (CAS 65853-80-7)
- Teprenone impurity 55 (CAS CATO-C4X-208155)
- Dacatavir impurity 36 (CAS 1007882-23-6)
- (R)-2-Ethylhexan-1-ol (CAS 50373-29-0)
- Neuroendocrine Regulatory Peptide-4 (human, mouse, rat) (H-7266.1000) (CAS 922704-18-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com