Lifitegrast Impurity 160 CAS CATO-C4X-2409160
| CAS No. | CATO-C4X-2409160 |
| Molecular Formula | C23H26Br2N2O5 |
| Molecular Weight | 570.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Lifitegrast Impurity 160 (C23H26Br2N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 570.27 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Lifitegrast Impurity 160 (CAS CATO-C4X-2409160, C23H26Br2N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lifitegrast Impurity 160 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H26Br2N2O5 |
| Molecular Weight | 570.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Lifitegrast Standards
- Lifitegrast Impurity 50 (CAS 2762168-17-0)
- lifitegrast Impurity 21 (CAS CATO-C4X-240921)
- Lifitegrast Impurity 146 (CAS CATO-C4X-2409146)
- Lifitegrast Impurity 16 (CAS 2322380-18-5)
- Lifitegrast Impurity 17 (CAS 2322380-15-2)
- Lifitegrast Impurity 66 (CAS CATO-C4X-240966)
- Lifitegrast Impurity 119 (CAS CATO-C4X-2409119)
- Lifitegrast Impurity 134 (CAS CATO-C4X-2409134)
Recommended Standards
- {3-[(2,4-dichlorobenzoyloxy)methyl]-4-oxo-3,4-dihydro-2H-1-benzothiopyran-3-yl}methyl 2,4-dichlorobenzoate (CAS 339028-82-9)
- N1,N4-Bis(4-bromophenyl)-N1,N4-diphenyl-1,4-benzenediamine (CAS 525602-17-9)
- Regorafenib Impurity 12 (CAS CATO-C4X-104712)
- 2,2'-(9,9-Dihexyl-9H-fluorene-2,7-diyl)bis(benzo[d][1,3,2]dioxaborole) (CAS 856570-41-7)
- Finerenone Impurity 111 (CAS CATO-C4X-2880111)
- Dalilesen Impurity 16 (CAS CATO-C4X-301016)
- Levocetirizine Impurity 24 (CAS 1232460-29-5)
- [(1-benzyl-4-methylpiperidin-4-yl)methyl](methyl)amine (CAS 403513-93-9)
- Glimepiride Impurity 16 (CAS 247098-17-5)
- 4-(5-(3,5-dihydroxyphenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)benzamide (CAS CATO-C4X-218055)
- 4-Iodo-7-methoxy-1H-pyrrolo[2,3-c]pyridine (CAS 1590409-79-2)
- cis-2-Boc-octahydrocyclopenta[c]pyrrole-5-carboxylic Acid (CAS 1069113-47-8)
- Dimethyl (E)-(3-Methyl-2-oxopent-3-en-1-yl)phosphonate (CAS 54543-04-3)
- 302798-54-5 (Leu31,Pro34)-Neuropeptide Y (13-36) (human, rat) MFCD00672463 (CAS 302798-54-5)
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