Lifitegrast Impurity 154 CAS CATO-C4X-2409154
| CAS No. | CATO-C4X-2409154 |
| Molecular Formula | C19H13BrClNO4 |
| Molecular Weight | 434.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Lifitegrast Impurity 154 (CAS CATO-C4X-2409154), a pharmacopoeial impurity reference standard (molecular formula C19H13BrClNO4, MW 434.67 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, Lifitegrast Impurity 154 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 434.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Lifitegrast Impurity 154 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H13BrClNO4 |
| Molecular Weight | 434.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 155 (CAS CATO-C4X-2409155)
- Lifitegrast Impurity 172 (CAS CATO-C4X-2409172)
- Lifitegrast Impurity 9 (CAS 1289646-72-5)
- Lifitegrast Impurity N27 (CAS 647037-87-4)
- Lifitegrast Impurity 159 (CAS CATO-C4X-2409159)
- Lifitegrast Impurity 164 (CAS CATO-C4X-2409164)
- Lifitegrast Impurity 169 (CAS CATO-C4X-2409169)
- Lifitegrast Impurity 45 (CAS CATO-C4X-240945)
Recommended Standards
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