Labetalol Impurity 65 CAS CATO-C4X-246665
| CAS No. | CATO-C4X-246665 |
| Molecular Formula | C11H15NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Labetalol Impurity 65 (CAS CATO-C4X-246665), a pharmacopoeial impurity reference standard (molecular formula C11H15NO4HCl, MW 261.70 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Labetalol Impurity 65 (C11H15NO4HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Labetalol Impurity 65 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H15NO4 HCl |
| Molecular Weight | 261.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Labetalol Standards
- Labetalol Impurity 29 (CAS 119021-71-5)
- Labetalol EP Impurity A (CAS 1391051-99-2)
- Labetalol Impurity 9 (CAS 22374-89-6)
- Labetalol EP Impurity C HCl (CAS 2386661-13-6)
- Labetalol-d5 HCl (CAS 2713514-78-2)
- Labetalol Impurity 23 (CAS 2724509-52-6)
- Labetalol Impurity 56 (CAS 2731858-23-2)
- Labetalol EP Impurity D HCl (CAS 32780-65-7)
Recommended Standards
- Omadacycline Impurity 30 (CAS CATO-C4X-285730)
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- Ibrutinib Impurity 136 (CAS 2190506-59-1)
- N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 (CAS 2107273-28-7)
- 2-Amino-3-methyl-N-((S)-1-methylpyrrolidin-3-yl)butanamide (CAS 1290229-51-4)
- 2,6-Di-Tert-Butylphenol (CAS 128-39-2)
- Metoprolol Impurity 19 (CAS 230975-30-1)
- 8-Chloro-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 103481-72-7)
- (1S)-1-[3-(difluoromethoxy)phenyl]ethan-1-ol (CAS 1315378-58-5)
- Sperm Activating Peptide, Sea Urchin (CAS 140653-27-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com