Labetalol Impurity 72 CAS CATO-C4X-246672
| CAS No. | CATO-C4X-246672 |
| Molecular Formula | C28H29N3O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Labetalol Impurity 72 (CAS CATO-C4X-246672), a pharmacopoeial impurity reference standard (molecular formula C28H29N3O6HCl, MW 540.01 g/mol) used for the identification and quantification of trace impurities in APIs.
Labetalol Impurity 72 (C28H29N3O6HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Labetalol Impurity 72 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H29N3O6 HCl |
| Molecular Weight | 540.01 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Labetalol Standards
- Labetalol Impurity 29 (CAS 119021-71-5)
- Labetalol EP Impurity A (CAS 1391051-99-2)
- Labetalol Impurity 9 (CAS 22374-89-6)
- Labetalol EP Impurity C HCl (CAS 2386661-13-6)
- Labetalol-d5 HCl (CAS 2713514-78-2)
- Labetalol Impurity 23 (CAS 2724509-52-6)
- Labetalol Impurity 56 (CAS 2731858-23-2)
- Labetalol EP Impurity D HCl (CAS 32780-65-7)
Recommended Standards
- Diltiazem Impurity 21 (CAS 42399-51-9)
- Naproxen Impurity 37 (CAS 676487-94-8)
- Kukoamine Impurity 6 (CAS CATO-C4X-22966)
- 2-(4-Phenylpiperazin-1-yl)quinazolin-4(3H)-one (CAS 129663-89-4)
- 5,5-Dimethyl-3,3a,4,5-tetrahydrocyclopenta[c]pyrazol-6(2H)-one (CAS 165686-37-3)
- (1R,2R,4S)-4-Amino-2-fluorocyclohexan-1-ol (CAS 2711860-19-2)
- (6-Methylpyridazin-4-yl)methanol (CAS 18591-52-1)
- 1-(6-(Difluoromethoxy)pyridin-3-yl)ethan-1-one (CAS 1198166-10-7)
- (S)-1-(2,3-difluorophenyl)-2-methoxyethan-1-amine (CAS 1270103-54-2)
- Palmitoyl Tripeptide -5 · 2 TFA (CAS 623172-56-5)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com