Diltiazem Impurity 21 CAS 42399-51-9
| CAS No. | 42399-51-9 |
| Molecular Formula | C16H15NO3S |
| Molecular Weight | 301.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Diltiazem Impurity 21 (CAS 42399-51-9), a pharmacopoeial impurity reference standard (molecular formula C16H15NO3S, MW 301.36 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Diltiazem Impurity 21 (C16H15NO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 301.36 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Diltiazem Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H15NO3S |
| Molecular Weight | 301.36 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Diltiazem Standards
- Diltiazem 2-Epimer O-Desacetyl N-Desdimethylaminoethyl Impurity (CAS 132830-17-2)
- Diltiazem Impurity 20 (CAS 132830-16-1)
- Diltiazem EP Impurity E (CAS 42399-49-5)
- Diltiazem Impurity N1 (CAS 42399-48-4)
- Diltiazem Impurity N2 (CAS 42399-50-8)
- Diltiazem Impurity 18 (CAS 131613-02-0)
- Diltiazem Impurity 23 (CAS 119009-50-6)
- Diltiazem Impurity 33 (CAS CATO-C4X-136833)
Recommended Standards
- Omeprazole Impurity 38 (CAS CATO-C4X-125538)
- Nebivolol Impurity 16 (CAS 99199-91-4)
- Tirofiban Impurity 9 (CAS 2250244-28-9)
- Nebivolol Impurity 56 (CAS CATO-C4X-196856)
- 2,4-Dichlorobenzyl Alcohol EP Impurity F (CAS 874-42-0)
- Mivacurium chloride Impurity 29 (CAS 53432-90-9)
- Latanoprost EP Impurity G (CAS 913258-31-8)
- Ethyl benzo[d]thiazole-4-carboxylate (CAS 2105183-05-7)
- Cyhalodiamide (CAS 1262605-53-7)
- 2-((8S,9R,10S,13R,14S,16R,17R)-9-Fluoro-17-hydroxy-13-(iodomethyl)-10,16-dimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate (CAS 1881-17-0)
- 3-(Heptafluorooctyl)aniline (CAS 119489-67-7)
- Rubber Oligomer 3 (CAS 2512216-71-4)
- Bismuth(III) titanate, 98% (CAS 12048-51-0)
- Gastric Inhibitory Polypeptide (1-30) amide (porcine) (CAS 134846-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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