Labetalol Hydrochloride EP Impurity F CAS CATO-C4X-246680
| CAS No. | CATO-C4X-246680 |
| Molecular Formula | C19H22N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Labetalol Hydrochloride EP Impurity F (C19H22N2O3HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Labetalol Hydrochloride EP Impurity F (CAS CATO-C4X-246680, C19H22N2O3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Labetalol Hydrochloride EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H22N2O3 HCl |
| Molecular Weight | 362.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Labetalol Standards
- Labetalol Impurity 29 (CAS 119021-71-5)
- Labetalol EP Impurity A (CAS 1391051-99-2)
- Labetalol Impurity 9 (CAS 22374-89-6)
- Labetalol EP Impurity C HCl (CAS 2386661-13-6)
- Labetalol-d5 HCl (CAS 2713514-78-2)
- Labetalol Impurity 23 (CAS 2724509-52-6)
- Labetalol Impurity 56 (CAS 2731858-23-2)
- Labetalol EP Impurity D HCl (CAS 32780-65-7)
Recommended Standards
- Minoxidil Impurity 60 (CAS CATO-C4X-170060)
- N-Nitroso Cinacalcet Impurity 9 (CAS CATO-C4X-105980)
- Trazodone Impurity 75 (CAS CATO-C4X-177275)
- Benzyl ((E)-3-oxo-3-(p-tolyl)prop-1-en-1-yl) cyanocarbonimidodithioate (CAS 275370-80-4)
- 8-Allyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 876921-17-4)
- 1-(2,4-dimethylphenyl)-5-(4-methoxyphenyl)-1H-imidazole-2-thiol (CAS 794554-71-5)
- 1-(2-Aminophenyl)piperidine-4-carboxamide (CAS 954587-51-0)
- 3-Bromo-2-(nitromethyl)pyridine (CAS 1379312-29-4)
- 5-(tert-Butoxy)-3-cyclopropoxypicolinic acid (CAS 1243441-03-3)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com