Labetalol EP Impurity E HCl CAS CATO-C4X-246681
| CAS No. | CATO-C4X-246681 |
| Molecular Formula | C18H20N4O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Labetalol EP Impurity E HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 392.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Labetalol EP Impurity E HCl (CAS CATO-C4X-246681) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20N4O4HCl and a molecular weight of 392.84 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Labetalol EP Impurity E HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20N4O4 HCl |
| Molecular Weight | 392.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Labetalol Standards
- Labetalol Impurity 29 (CAS 119021-71-5)
- Labetalol EP Impurity A (CAS 1391051-99-2)
- Labetalol Impurity 9 (CAS 22374-89-6)
- Labetalol EP Impurity C HCl (CAS 2386661-13-6)
- Labetalol-d5 HCl (CAS 2713514-78-2)
- Labetalol Impurity 23 (CAS 2724509-52-6)
- Labetalol Impurity 56 (CAS 2731858-23-2)
- Labetalol EP Impurity D HCl (CAS 32780-65-7)
Recommended Standards
- Lomustine EP Impurity B (CAS 13908-11-7)
- Milrinone Impurity 35 (CAS 52600-51-8)
- Paracetamol EP Impurity I (CAS 118-93-4)
- [5-(4-Bromobenzenesulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl 4-chlorobenzoate (CAS 318239-68-8)
- H-Thr-Asn-Arg-Asn-Phe-Leu-Arg-Phe-NH2 (CAS 113611-68-0)
- 2-Hydroxy-3-propylhexanoic acid (CAS 1515602-22-8)
- 5-(Naphthalen-2-yl)-1h-pyrazole-3-carboxylic acid (CAS 164295-94-7)
- N3-(4-Methylphenyl)-1H-1,2,4-triazole-3,5-diamine (CAS 3929-18-8)
- 2-(Aminomethyl)-3-(difluoromethyl)-6-fluoro-4-nitropyridine (CAS 1806974-47-9)
- Des-Leu26-Tirzepatide (CAS CATO-CPTD788947)
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