Rimegepant Impurity 11 CAS CATO-C4X-248711
| CAS No. | CATO-C4X-248711 |
| Molecular Formula | C25H32FNO2Si |
| Molecular Weight | 425.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Rimegepant Impurity 11 (CAS CATO-C4X-248711, C25H32FNO2Si) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Rimegepant Impurity 11 (C25H32FNO2Si) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rimegepant Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H32FNO2Si |
| Molecular Weight | 425.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Rimegepant Standards
- Rimegepant Impurity 10 (CAS CATO-C4X-248710)
- Rimegepant Impurity 76 (CAS CATO-C4X-248776)
- Rimegepant Impurity 77 (CAS CATO-C4X-248777)
- Rimegepant Impurity 88 (CAS CATO-C4X-248788)
- Rimegepant Impurity 89 (CAS CATO-C4X-248789)
- Rimegepant Impurity 90 (CAS CATO-C4X-248790)
- Rimegepant Impurity 91 (CAS CATO-C4X-248791)
- Rimegepant Impurity 130 (CAS CATO-C4X-2487130)
Recommended Standards
- (5E)-3-Benzyl-5-{[2-(cyclohexylsulfanyl)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 273731-76-3)
- N'-((2-Oxo-1,2-dihydroquinolin-3-yl)methylene)palmitohydrazide (CAS 881664-42-2)
- C18:1 (Δ9-cis)carnitine (CAS 13962-05-5)
- 4-Chloro-5-iodo-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 847551-48-8)
- Pimavanserin Impurity 10 (CAS CATO-C4X-193810)
- Salbutamol EP Impurity A HCl (CAS 2468639-65-6)
- Paclitaxel Impurity 58 (CAS CATO-C4X-184258)
- (4-Aminopyridin-2-yl)boronic acid (CAS 1310404-05-7)
- 7-Methoxy-1,8-naphthyridin-2-amine (CAS 53788-35-5)
- (3S,5S)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-hydroxy-cyclohexanemethanol (CAS 139356-34-6)
- 4-(aminomethyl)-N-(4-fluorophenyl)benzamide (CAS 953886-01-6)
- Methotrexate Impurity 34 (CAS CATO-C4X-115434)
- 2-Chloro-3-(trifluoromethyl)phenylboronic acid pinacol ester (CAS 1689550-75-1)
- Semaglutide impurity 29 (CAS 1188328-22-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com