Paclitaxel Impurity 58 CAS CATO-C4X-184258
| CAS No. | CATO-C4X-184258 |
| Molecular Formula | C45H55NO14 |
| Molecular Weight | 833.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Paclitaxel Impurity 58 (CAS CATO-C4X-184258) is a certified pharmaceutical impurity reference standard with the molecular formula C45H55NO14 and a molecular weight of 833.92 g/mol.
The molecular framework of Paclitaxel Impurity 58 (C45H55NO14) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C45H55NO14 |
| Molecular Weight | 833.92 g/mol |
| Purity | 95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Paclitaxel Standards
- Paclitaxel EP Impurity R (CAS 158948-96-0)
- Paclitaxel Impurity R (CAS 159001-25-9)
- Paclitaxel Impurity 38 (CAS 173101-55-8)
- Paclitaxel Impurity 61 (CAS CATO-C4X-184261)
- Paclitaxel Impurity 62 (CAS CATO-C4X-184262)
- Paclitaxel EP Impurity A (CAS 173101-54-7)
- Paclitaxel Impurity 18 (CAS CATO-C4X-184218)
- Paclitaxel EP Impurity B (CAS 71610-00-9)
Recommended Standards
- 2-Debenzoyl Paclitaxel 2-Pentanoate (CAS 213767-22-7)
- PDI-CC6C6-Br (CAS 259880-25-6)
- 213539-42-5 Benzenepropanoic acid, alpha-hydroxy-beta-((2-methyl-1-oxobutyl)amino)-, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (alphaR,betaS)- Taxoline (CAS 213539-42-5)
- Venetoclax Impurity 8 (CAS 2573767-91-4)
- Isavuconazole Impurity 37 Chloride DiHCl (Mixture of Diastereomers) (CAS CATO-C4X-123637)
- Levocarnitine Impurity 30 (D-Camphoric Acid) (CAS 124-83-4)
- Citalopram Impurity 85 (CAS CATO-C4X-110985)
- 5-(3-Isopropylbenzyl)thiazol-2-amine (CAS 923813-16-5)
- (E)-3-(2,3-Dimethoxyphenyl)prop-2-en-1-amine (CAS 1315377-90-2)
- 8-Oxabicyclo[3.2.1]octan-3-ylmethanol (CAS 1781031-03-5)
- 3-Methyl-7-methoxy-8-(chloromethyl)flavone (CAS 25782-05-2)
- (1-Methyl-1H-indol-6-yl)methanamine (CAS 864264-03-9)
- rel-(1R,6R)-6-(methoxycarbonyl)cyclohex-3-ene-1-carboxylic acid (CAS 31139-03-4)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
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