Rimegepant Impurity 24 CAS CATO-C4X-248724
| CAS No. | CATO-C4X-248724 |
| Molecular Formula | C16H12ClF2N |
| Molecular Weight | 291.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Rimegepant Impurity 24 (C16H12ClF2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 291.72 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Rimegepant Impurity 24 (CAS CATO-C4X-248724, C16H12ClF2N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Rimegepant Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12ClF2N |
| Molecular Weight | 291.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Rimegepant Standards
- Rimegepant Impurity 31 (CAS CATO-C4X-248731)
- Rimegepant Impurity 74 (CAS CATO-C4X-248774)
- Rimegepant Impurity 63 (CAS 1071154-76-1)
- Rimegepant Impurity 139 (CAS CATO-C4X-2487139)
- Rimegepant Impurity 101 (CAS CATO-C4X-2487101)
- Rimegepant Impurity 124 (CAS CATO-C4X-2487124)
- Rimegepant Impurity 128 (CAS CATO-C4X-2487128)
- Rimegepant Impurity 38 (CAS 1373116-05-2)
Recommended Standards
- 317318-97-1 4-[5-(Chloromethyl)-4-methyl-1,3-thiazol-2-yl]benzotrifluoride 5-(chloromethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole (CAS 317318-97-1)
- 4-Chloro-3-hydroxy-N-(3-methyl-1-phenyl-1h-pyrazol-5-yl)but-2-enamide (CAS 1006492-92-7)
- Thiamethoxam (CAS 153719-23-4)
- 3-Chloro-1-oxo-2-(tetrahydrofuran-2-ylmethyl)isoquinoline-4-carbaldehyde (CAS 1018250-86-6)
- Safinamide Impurity 25 (CAS CATO-C4X-159025)
- Azathioprine Impurity 26 (CAS 18753-82-7)
- Alprazolam EP Impurity F (CAS 37945-07-6)
- 1-(5-Bromo-6-fluoro-1-indazolyl)ethanone (CAS 633335-81-6)
- 1-(3-Methylbut-2-en-1-yl)quinazolin-4(1H)-one (CAS 28751-77-1)
- 2-(2-Brom-3-fluorophenyl)-1,3-dioxolane (CAS 2169687-26-5)
- 3-Bromomethyl-2-fluorobenzeneboronic acid pinacol ester, 97% (CAS 1256360-37-8)
- 1-Cyano-4-ethylcyclohexane-1-carboxylic acid (CAS 1503909-72-5)
- Betaxolol EP Impurity E (CAS 1329613-85-5)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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