Dotinurad Impurity 178 CAS CATO-C4X-2494178
| CAS No. | CATO-C4X-2494178 |
| Molecular Formula | C16H12ClNO3S |
| Molecular Weight | 333.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Dotinurad Impurity 178 (CAS CATO-C4X-2494178) is a certified pharmaceutical impurity reference standard with the molecular formula C16H12ClNO3S and a molecular weight of 333.79 g/mol.
The molecular framework of Dotinurad Impurity 178 (C16H12ClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Dotinurad Impurity 178 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H12ClNO3S |
| Molecular Weight | 333.79 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dotinurad Standards
- Dotinurad Impurity 218 (CAS CATO-C4X-2494218)
- Dotinurad Impurity 166 (CAS CATO-C4X-2494166)
- Dotinurad Impurity 233 (CAS CATO-C4X-2494233)
- Dotinurad Impurity 181 (CAS 425666-79-1)
- Dotinurad Impurity 219 (CAS CATO-C4X-2494219)
- Dotinurad Impurity 30 (CAS CATO-C4X-249430)
- Dotinurad Impurity 159 (CAS CATO-C4X-2494159)
- Dotinurad Impurity 36 (CAS 532963-00-1)
Recommended Standards
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- N-[2-Chloro-5-(Trifluoromethyl)Phenyl]-2-Hydroxy-3-Nitrobenzamide (CAS 33713-13-2)
- 4-Ethynyl-2-fluoro-1-nitrobenzene (CAS 2229532-54-9)
- 6-Bromo-3-chloro-2-nitropyridine (CAS 1805485-96-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com