Tucatinib Impurity 1 CAS CATO-C4X-26051

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-26051
Molecular FormulaC26H24N8OS
Molecular Weight496.59 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tucatinib Impurity 1 CAS CATO-C4X-26051 chemical structure

Description

CATO supplies Tucatinib Impurity 1 (CAS CATO-C4X-26051), a pharmacopoeial impurity reference standard (molecular formula C26H24N8OS, MW 496.59 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C26H24N8OS, Tucatinib Impurity 1 contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 496.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Tucatinib Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC26H24N8OS
Molecular Weight496.59 g/mol
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)19.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms8
Sulfur Atoms1

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