Tucatinib Impurity 5 CAS CATO-C4X-26055
| CAS No. | CATO-C4X-26055 |
| Molecular Formula | C26H24N8OS |
| Molecular Weight | 496.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tucatinib Impurity 5 is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Tucatinib Impurity 5 (CAS CATO-C4X-26055, C26H24N8OS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Tucatinib Impurity 5 (C26H24N8OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tucatinib Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H24N8OS |
| Molecular Weight | 496.59 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 1 |
Related Tucatinib Standards
- Tucatinib Impurity 1 (CAS CATO-C4X-26051)
- Tucatinib Impurity 16 (CAS CATO-C4X-260516)
- Tucatinib Impurity 2 (CAS CATO-C4X-26052)
- Tucatinib Impurity 3 (CAS CATO-C4X-26053)
- Tucatinib Impurity 4 (CAS CATO-C4X-26054)
- Tucatinib Impurity 39 (CAS CATO-C4X-260539)
- Tucatinib Impurity 58 (CAS CATO-C4X-260558)
- Tucatinib Impurity 15 (CAS CATO-C4X-260515)
Recommended Standards
- (S)-tert-butyl 2-(4-(3-ethylureido)phenyl)-4-(3-methylmorpholino)-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate (CAS 1207365-47-6)
- Benzyl (2S)-2-[(4-{[(tert-butoxy)carbonyl]amino}-1-(pyridin-2-yl)butyl)carbamoyl]pyrrolidine-1-carboxylate (CAS 1276017-65-2)
- 4,4′-[1,4-Phenylenebis[(4-methylphenyl)imino]]bis[benzaldehyde] (CAS 131660-39-4)
- Bis[bis(3,5-dimethylphenyl)phosphino]methane (CAS 167109-95-7)
- Lanreotide Impurity 12 (CAS CATO-C4X-237012)
- N-Nitroso Bupropion 3,5-Dichloro Impurity 64 (CAS CATO-C4X-120364)
- Tandospirone Impurity 16 Citrate (CAS CATO-C4X-187517)
- (6-fluoroimidazo[1,2-a]pyridin-3-yl)methanol (CAS 1520373-01-6)
- 4-Chloro-N-(6-nitrobenzo[d]thiazol-2-yl)benzamide (CAS 321943-75-3)
- 1-Amino-4-isopropylcyclohexane-1-carbonitrile (CAS 804433-45-2)
- (R)-Fmoc-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 204317-98-6)
- 3-ethyl-2,3-dihydro-1H-indol-2-one (CAS 15379-45-0)
- N-(3-Cyanothiophen-2-yl)-4-(ethylthio)benzamide (CAS 898446-66-7)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com