Tucatinib Impurity 14 CAS CATO-C4X-260514
| CAS No. | CATO-C4X-260514 |
| Molecular Formula | C24H22N8OS |
| Molecular Weight | 470.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tucatinib Impurity 14 (CAS CATO-C4X-260514) is a certified pharmaceutical impurity reference standard with the molecular formula C24H22N8OS and a molecular weight of 470.55 g/mol.
The molecular framework of Tucatinib Impurity 14 (C24H22N8OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tucatinib Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H22N8OS |
| Molecular Weight | 470.55 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 1 |
Related Tucatinib Standards
- Tucatinib Impurity 33 (CAS CATO-C4X-260533)
- Tucatinib Impurity 34 (CAS CATO-C4X-260534)
- Tucatinib (CAS 937263-43-9)
- Tucatinib Impurity 54 (CAS CATO-C4X-260554)
- Tucatinib Impurity 49 (CAS CATO-C4X-260549)
- Tucatinib D6 (CAS CATO-C4X-260540)
- Tucatinib Impurity 58 (CAS CATO-C4X-260558)
- Tucatinib Impurity 39 (CAS CATO-C4X-260539)
Recommended Standards
- Fluorometholone Impurity 7 (CAS 2796-99-8)
- 2,6-Bis((4-ethylbenzylidene)amino)anthracene-9,10-dione (CAS 106159-41-5)
- Beclometasone Impurity 53 (CAS CATO-C4X-147453)
- 2-(10-(Naphthalen-1-yl)anthracen-9-yl)dibenzo[b,d]furan (CAS 1226809-42-2)
- Paliperidone Impurity 87 (CAS CATO-C4X-172487)
- Plerixafor Impurity 10 (CAS 80413-59-8)
- Enzalutamide Impurity 59 (CAS CATO-C4X-101659)
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- 3-(Difluoromethyl)-5-methyl-1H-pyrazole (CAS 936033-61-3)
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- Methyl 5-(2-fluoro-5-methoxyphenyl)-4-(hydroxymethyl)-2-methylpyrrolidine-2-carboxylate (CAS 1217831-96-3)
- Neuropeptide GE (CAS 134748-04-2)
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