Tucatinib Impurity 34 CAS CATO-C4X-260534
| CAS No. | CATO-C4X-260534 |
| Molecular Formula | C26H22N8O2 |
| Molecular Weight | 478.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Tucatinib Impurity 34 (CAS CATO-C4X-260534), a pharmacopoeial impurity reference standard (molecular formula C26H22N8O2, MW 478.51 g/mol) used for the identification and quantification of trace impurities in APIs.
Tucatinib Impurity 34 (C26H22N8O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Tucatinib Impurity 34 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H22N8O2 |
| Molecular Weight | 478.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Tucatinib Standards
- Tucatinib (CAS 937263-43-9)
- Tucatinib Impurity 33 (CAS CATO-C4X-260533)
- Tucatinib Impurity 54 (CAS CATO-C4X-260554)
- Tucatinib Impurity 14 (CAS CATO-C4X-260514)
- Tucatinib D6 (CAS CATO-C4X-260540)
- Tucatinib Impurity 58 (CAS CATO-C4X-260558)
- Tucatinib Impurity 39 (CAS CATO-C4X-260539)
- Tucatinib Impurity 1 (CAS CATO-C4X-26051)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com