Pretomanid Impurity 12 CAS CATO-C4X-260612
| CAS No. | CATO-C4X-260612 |
| Molecular Formula | C15H14F3N3O5 |
| Molecular Weight | 373.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Pretomanid Impurity 12 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 373.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Pretomanid Impurity 12 (CAS CATO-C4X-260612) is a certified pharmaceutical impurity reference standard with the molecular formula C15H14F3N3O5 and a molecular weight of 373.28 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Pretomanid Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14F3N3O5 |
| Molecular Weight | 373.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ＞95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Pretomanid Standards
- Pretomanid Impurity 6 (CAS CATO-C4X-26066)
- Pretomanid-4d (CAS 1346617-34-2)
- Pretomanid (CAS 187235-37-6)
- Pretomanid Impurity 15 (CAS 1353753-57-7)
- Pretomanid Impurity 16 (CAS CATO-C4X-260616)
- Pretomanid Impurity 2 (CAS 1105708-11-9)
- Pretomanid Impurity 4 (CAS 1131004-99-3)
- Pretomanid Impurity 8 (CAS CATO-C4X-26068)
Recommended Standards
- 7-Chloro-1-(2-chlorophenyl)-N,N-diethylisoquinoline-3-carboxamide (CAS 89242-33-1)
- Luliconazole impurity 20 (CAS CATO-C4X-285320)
- 3-(2,6-Dichlorobenzyl)-2-methyl-1-(2-(pyridin-2-yl)ethyl)pyridin-4(1H)-one (CAS 400736-56-3)
- Relmapirazin impurity 7 (CAS CATO-C4X-33347)
- Cinacalcet Impurity 26 (CAS 1201-74-7)
- Relebactam Impurity 147 (CAS CATO-C4X-2144147)
- Tucatinib Impurity 46 (CAS CATO-C4X-260546)
- tert-butyl 2-amino-4-(dimethoxymethyl)-1H-imidazole-1-carboxylate (CAS 917919-48-3)
- Ethyl2-morpholinoisonicotinate (CAS 883107-57-1)
- 6-Methoxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-one (CAS 137075-36-6)
- 1-(4-methoxyphenyl)-2-[(1-phenylpropan-2-yl)amino]ethan-1-ol (CAS 1409070-36-5)
- 3-[(Dimethylamino)methyl]benzenethiolhydrochloride (CAS 128457-54-5)
- Cefixime Impurity 105 (CAS CATO-C4X-1139105)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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