Pretomanid Impurity 29 CAS CATO-C4X-260629
| CAS No. | CATO-C4X-260629 |
| Molecular Formula | C14H11BrF3N3O5 |
| Molecular Weight | 438.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Pretomanid Impurity 29 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Pretomanid Impurity 29 (CAS CATO-C4X-260629, C14H11BrF3N3O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C14H11BrF3N3O5, Pretomanid Impurity 29 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 438.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H11BrF3N3O5 |
| Molecular Weight | 438.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Pretomanid Standards
- Pretomanid Impurity 7 (CAS CATO-C4X-26067)
- Pretomanid Impurity 19 (CAS CATO-C4X-260619)
- Pretomanid Impurity 14 (CAS CATO-C4X-260614)
- Pretomanid Impurity 28 (CAS 2512206-85-6)
- Pretomanid Impurity 6 (CAS CATO-C4X-26066)
- Pretomanid Impurity 12 (CAS CATO-C4X-260612)
- Pretomanid-4d (CAS 1346617-34-2)
- Pretomanid (CAS 187235-37-6)
Recommended Standards
- Dimethyl 2,2'-(adamantane-1,3-diyl)bis(2-bromoacetate) (CAS 202534-05-2)
- 4-Chloro-n-(2,2,2-trichloro-1-(1h-indol-3-yl)ethyl)benzenesulfonamide (CAS 348642-53-5)
- 4,4′-Dibromo-2,2′,3,3′-tetrahydro-7,7′-dimethoxy-1,1′-spirobi[1H-indene] (CAS 223137-76-6)
- Bis(3-bromo-1,2,4-thiadiazol-5-ylsulfinyl)methane (CAS 845879-07-4)
- Nerandomilast impurity 4 (CAS CATO-C4X-34734)
- Telmisartan Impurity 83 (CAS CATO-C4X-135983)
- Alogliptin impurity 13 (CAS 2749281-73-8)
- 3-(Adamantan-1-yl)-1-ethylguanidine (CAS 803619-71-8)
- (1-Methyl-1H-indazol-3-yl)methanamine dihydrochloride (CAS 1093860-45-7)
- Methyl 3,4,5-trichlorobenzoate (CAS 114821-66-8)
- N-(Naphthalen-1-yl)isoxazole-5-carboxamide (CAS 941993-96-0)
- Valaciclovir EP Impurity O (CAS CATO-C4X-124819)
- rel-((1R,3r,5S)-tert-Butyl 3-formyl-8-azabicyclo[3.2.1]octane-8-carboxylate) (CAS 882041-98-7)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
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