Pretomanid Impurity 19 CAS CATO-C4X-260619
| CAS No. | CATO-C4X-260619 |
| Molecular Formula | C16H24BrN3O6 |
| Molecular Weight | 434.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Pretomanid Impurity 19 (CAS CATO-C4X-260619), a pharmacopoeial impurity reference standard (molecular formula C16H24BrN3O6, MW 434.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Pretomanid Impurity 19 (C16H24BrN3O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H24BrN3O6 |
| Molecular Weight | 434.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Pretomanid Standards
- Pretomanid Impurity 29 (CAS CATO-C4X-260629)
- Pretomanid Impurity 7 (CAS CATO-C4X-26067)
- Pretomanid Impurity 14 (CAS CATO-C4X-260614)
- Pretomanid Impurity 28 (CAS 2512206-85-6)
- Pretomanid Impurity 6 (CAS CATO-C4X-26066)
- Pretomanid Impurity 12 (CAS CATO-C4X-260612)
- Pretomanid-4d (CAS 1346617-34-2)
- Pretomanid (CAS 187235-37-6)
Recommended Standards
- N-(4-((4-bromophenyl)sulfonyl)phenyl)-4-fluorobenzamide (CAS 339104-62-0)
- (3-(2,6-Dichlorophenyl)-5-methylisoxazol-4-yl)(4-(2-fluorophenyl)piperazin-1-yl)methanone (CAS 442564-97-8)
- 4-Bromophenyl 2-(4-methoxyphenyl)quinoline-4-carboxylate (CAS 332381-29-0)
- {4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methyl 3-chlorobenzoate (CAS 320424-11-1)
- Ramelteon impurity 45 (CAS CATO-C4X-262245)
- Venlafaxine Impurity 13 (CAS CATO-C4X-143413)
- Dotinurad Impurity 67 (CAS 39884-80-5)
- 6-Bromo-2-(pyrrolidin-3-yl)isoindolin-1-one (CAS 1443285-83-3)
- 3-Cyclopentyl-1-(3-methylpiperazin-1-yl)propan-1-one (CAS 1240564-99-1)
- 2-Amino-4-(4-chlorophenyl)butanoic acid (CAS 225233-78-3)
- 2-(4-(Chloromethyl)phenyl)-5-fluoropyrimidine (CAS 1139432-30-6)
- O-(3-(tert-butyl)phenyl) carbonochloridothioate (CAS 97986-06-6)
- 6-Nitrochroman-4-one (CAS 68043-53-8)
- (Met(O)2?)-Glucagon (1-29) (human, rat, porcine) (CAS 75217-63-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com