Raltegravir 5-Methoxy Impurity CAS CATO-C4X-26158
| CAS No. | CATO-C4X-26158 |
| Molecular Formula | C20H21FN6O5 |
| Molecular Weight | 444.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Raltegravir 5-Methoxy Impurity (CAS CATO-C4X-26158), a pharmacopoeial impurity reference standard (molecular formula C20H21FN6O5, MW 444.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H21FN6O5, Raltegravir 5-Methoxy Impurity contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 444.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Raltegravir 5-Methoxy Impurity meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21FN6O5 |
| Molecular Weight | 444.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Raltegravir Standards
- Raltegravir (CAS 518048-05-0)
- Raltegravir -D6 (CAS 1100750-98-8)
- Raltegravir Impurity15 (CAS 519028-33-2)
- Raltegravir EP Impurity E (CAS 1193687-87-4)
- Raltegravir EP Impurity C (CAS 1391918-17-4)
- Raltegravir Diketo Ethoxy Impurity (CAS 1193687-88-5)
- Raltegravir Impurity 9 (CAS 518048-02-7)
- Raltegravir EP Impurity D (CAS 1064706-98-4)
Recommended Standards
- Tedizolid Impurity 51 (CAS CATO-C4X-105451)
- Tetraethyl [4,4'-bipyridine]-2,2',6,6'-tetracarboxylate (CAS 124558-63-0)
- 1-(2-((3-(Thiophen-2-yl)-1,2,4-oxadiazol-5-yl)methyl)phenyl)-3-(2-(trifluoromethyl)phenyl)urea (CAS 1797268-13-3)
- 2-Benzoyl-3-{[3-(trifluoromethyl)benzenesulfonyl]methyl}-1-benzofuran (CAS 338423-88-4)
- Degarelix Impurity 5 (CAS CATO-C4X-21365)
- Ibrutinib Impurity 191 (CAS CATO-C4X-1064191)
- Upadacitinib Impurity 33 (CAS 2650489-66-8)
- 4-(4-Methylpiperazin-1-yl)benzoic acidhydrochloride (CAS 289044-60-6)
- 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-7-carboxylic acid (CAS 1094107-96-6)
- [(S)-1-(2-Amino-ethyl)-pyrrolidin-2-ylmethyl]-ethyl-carbamic acid benzyl ester (CAS 1353982-22-5)
- 4-((1E,3E)-4-(4-(dimethylamino)phenyl)buta-1,3-dien-1-yl)-1-methylpyridin-1-ium perchlorate (CAS 89846-21-9)
- 8-Chloro-2-(methylsulfonyl)pyrimido[5,4-d]pyrimidine (CAS 1824276-64-3)
- (2R)-2-(chloromethyl)oxetane (CAS 1107646-00-3)
- Liraglutide Impurity 21 TFA Salt (CAS CATO-C4X-199221)
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