Erdafitinib Impurity 12 CAS CATO-C4X-261612
| CAS No. | CATO-C4X-261612 |
| Molecular Formula | C8H4Br2N2O |
| Molecular Weight | 303.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Erdafitinib Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Erdafitinib Impurity 12 (CAS CATO-C4X-261612), a pharmacopoeial impurity reference standard (molecular formula C8H4Br2N2O, MW 303.94 g/mol) used for the identification and quantification of trace impurities in APIs.
Erdafitinib Impurity 12 (C8H4Br2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H4Br2N2O |
| Molecular Weight | 303.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Erdafitinib Standards
- Erdafitinib Impurity 2 (CAS 123342-12-1)
- Erdafitinib Impurity 3 (CAS 380639-03-2)
- Erdafitinib Impurity 4 (CAS 2731009-66-6)
- Erdafitinib Impurity 10 (CAS 2839751-66-3)
- Erdafitinib Impurity 13 (CAS 1346244-83-4)
- Erdafitinib Impurity 11 (CAS 1346243-54-6)
- Erdafitinib Impurity 14 (CAS CATO-C4X-261614)
- Erdafitinib Impurity 1 (CAS 40534-39-2)
Recommended Standards
- 5,7-Dibromoquinazolin-4(3H)-one (CAS 860192-99-0)
- 4,6-Dibromophthalazin-1(2H)-one (CAS 2750149-30-3)
- 2,4-Dibromo-3,5-difluorobenzenethiol (CAS 1208077-53-5)
- 4,6-Dibromo-1H-indazole-3-carboxaldehyde (CAS 885518-57-0)
- Diflorasone impurity 2 (CAS CATO-C4X-24802)
- Avibactam impurity 113 (CAS 115134-37-7)
- Bevantolol Impurity 4 (CAS CATO-C4X-24114)
- FMOC-Ala-Leu-OH (CAS 177609-08-4)
- N-(3-Amino-2-methylphenyl)-2-(4-chloro-3,5-dimethylphenoxy)acetamide (CAS 1020056-26-1)
- 2-(4-Isopropoxyphenyl)propan-2-amine (CAS 1225845-98-6)
- N-(1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)hydroxylamine (CAS 124489-20-9)
- N-(4-(5-(4-Fluorophenyl)-1-((4-methoxyphenyl)sulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide (CAS 851781-48-1)
- 1-(6-(4-Bromophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)ethanamine (CAS 1706455-30-2)
- Des-Ser39-Tirzepatide (CAS CATO-CPTD788936)
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