Apalutamide Impurity 118 CAS CATO-C4X-2749118
| CAS No. | CATO-C4X-2749118 |
| Molecular Formula | C12H8F2O4 |
| Molecular Weight | 254.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Apalutamide Impurity 118 (CAS CATO-C4X-2749118), a pharmacopoeial impurity reference standard (molecular formula C12H8F2O4, MW 254.19 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Apalutamide Impurity 118 (C12H8F2O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 254.19 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8F2O4 |
| Molecular Weight | 254.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Apalutamide Standards
- Apalutamide Impurity 24 (CAS CATO-C4X-274924)
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- Apalutamide Impurity 66 (CAS CATO-C4X-274966)
- Apalutamide Impurity 34 (CAS CATO-C4X-274934)
Recommended Standards
- Phloroglucinol impurity 53 (CAS CATO-C4X-221753)
- Finerenone Impurity 115 (CAS 65582-57-2)
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- Finerenone Impurity 172 (CAS CATO-C4X-2880172)
- Finerenone Impurity 267 (CAS CATO-C4X-2880267)
- Oxacillin Impurity 44 (CAS CATO-C4X-232144)
- Prucalopride Impurity 27 (CAS CATO-C4X-103827)
- 5-Amino-2,3-dihydrobenzofuran-7-carboxamide (CAS 1616110-55-4)
- (R)-1-(4-Bromophenyl)propan-1-amine (CAS 856758-61-7)
- 5-(3-Acetylphenyl)furan-2-carbaldehyde (CAS 637728-09-7)
- N-cyclopropyl-4-iodo-1-methyl-1H-pyrazole-5-carboxamide (CAS 1005553-41-2)
- (2-Methoxy-6-nitrophenyl)methanol (CAS 19689-87-3)
- 6-Amino-3-bromo-2-chlorobenzoic acid (CAS 3030-19-1)
- Peptide 440 (CAS CATO-CPTD788440)
Why CATO?
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