Apalutamide Impurity 69 CAS CATO-C4X-274969
| CAS No. | CATO-C4X-274969 |
| Molecular Formula | C21H17F4N5O3 |
| Molecular Weight | 463.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Apalutamide Impurity 69 (C21H17F4N5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Apalutamide Impurity 69 (CAS CATO-C4X-274969) is a certified pharmaceutical impurity reference standard with the molecular formula C21H17F4N5O3 and a molecular weight of 463.38 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Apalutamide Impurity 69 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H17F4N5O3 |
| Molecular Weight | 463.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Apalutamide Standards
- Apalutamide Impurity 6 (CAS 1332391-11-3)
- Apalutamide Acid (CAS 1332391-04-4)
- Apalutamide Impurity 11 (CAS 1332391-92-0)
- Apalutamide Impurity 54 (CAS 1332389-57-7)
- Apalutamide Impurity 101 (CAS CATO-C4X-2749101)
- Apalutamide Impurity 75 (CAS CATO-C4X-274975)
- Apalutamide impurity 84 (CAS CATO-C4X-274984)
- Apalutamide Impurity 56 (CAS CATO-C4X-274956)
Recommended Standards
- N-Benzhydryl-2-((2,5-dichloro-N-methylphenyl)sulfonamido)acetamide (CAS 847773-02-8)
- 4-Nitrophenyl-beta-D-melibioside (CAS 104872-92-6)
- N-[(1E)-{[(3-fluorophenyl)methoxy]imino}methyl]-4-methoxy-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide (CAS 478262-37-2)
- 4-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-3-iodo-5-nitropyridine (CAS 1186310-82-6)
- Phenytoin Impurity 16 (CAS CATO-C4X-186416)
- Cimetidine Impurity 9 (CAS 38603-74-6（free base）)
- Baricitinib Impurity 8 (CAS 2402776-84-3)
- 4-(Cyclopropylmethoxy)piperidine (CAS 865106-51-0)
- 7-Chloro-8-methyl-2-(3-propoxyphenyl)quinoline-4-carboxylic acid (CAS 863185-11-9)
- (5-cyanothiophen-3-yl)boronic acid (CAS 1065184-99-7)
- 1-(tert-Butyl) 5-methyl 3-(2-aminoethyl)-1H-indole-1,5-dicarboxylate hydrochloride (CAS 1171456-52-2)
- 3-amino-1$l^{6}-benzothiophene-1,1-dione (CAS 858819-96-2)
- (S)-5-(Azetidin-2-ylmethoxy)pyrimidine (CAS 228866-56-6)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com