N-[(1E)-{[(3-fluorophenyl)methoxy]imino}methyl]-4-methoxy-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide CAS 478262-37-2
| CAS No. | 478262-37-2 |
| Molecular Formula | C22H17F4N3O4 |
| Molecular Weight | 463.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-[(1E)-{[(3-fluorophenyl)methoxy]imino}methyl]-4-methoxy-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide (CAS 478262-37-2), a certified reference material (molecular formula C22H17F4N3O4, MW 463.38 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N-[(1E)-{[(3-fluorophenyl)methoxy]imino}methyl]-4-methoxy-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 463.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), N-[(1E)-{[(3-fluorophenyl)methoxy]imino}methyl]-4-methoxy-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H17F4N3O4 |
| Molecular Weight | 463.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- N-[(1E)-{[(2-fluorophenyl)methoxy]imino}methyl]-4-methoxy-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide (CAS 478262-39-4)
- N-Benzhydryl-2-((2,5-dichloro-N-methylphenyl)sulfonamido)acetamide (CAS 847773-02-8)
- 3,4-Dihydroxy-9,10-dioxo-N-(4-(trifluoromethyl)-phenyl)-9,10-dihydroanthracene-2-sulfonamide (CAS 1313738-90-7)
- Apalutamide Impurity 69 (CAS CATO-C4X-274969)
- 5-Bromo-2-difluoromethoxy-3-fluorophenol (CAS 1805525-80-7)
- Methyl 5-(4-ethoxybenzoyl)furan-2-carboxylate (CAS 1399658-44-6)
- Methyl 3-fluoro-5-(trifluoromethoxy)benzoate (CAS 1806334-89-3)
- (2S,3S,4S,5S)-3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-carboxylic acid (CAS 2538633-95-1)
- 2-(3-Chlorophenyl)-2,2-difluoroacetonitrile (CAS 1334146-06-3)
- Gadoxetate impurity 21 (CAS CATO-C4X-261821)
- 6-((4-Bromophenyl)amino)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide (CAS 7357-33-7)
- (±)-cis,trans-Abscisic Acid Glucosyl Ester (CAS 79199-48-7)
- 3-(3-Chloro-4-fluorophenyl)-1H-pyrazol-5-amine (CAS 1313910-84-7)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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