Coclaurine Impurity 7 CAS CATO-C4X-27517
| CAS No. | CATO-C4X-27517 |
| Molecular Formula | C19H23NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Coclaurine Impurity 7 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Coclaurine Impurity 7 (CAS CATO-C4X-27517, C19H23NO3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Coclaurine Impurity 7 (C19H23NO3HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Coclaurine Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H23NO3 HCl |
| Molecular Weight | 349.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Coclaurine Standards
- Coclaurine Impurity 112 (CAS 116331-72-7)
- Coclaurine Impurity 2 HCl (CAS 13233-00-6)
- Coclaurine Related Compound 1 (CAS 138644-99-2)
- (±)-Coclaurine HCl (CAS 17934-80-4)
- (R)-Coclaurine HCl (CAS 19894-19-0)
- Coclaurine Impurity 113 (CAS 2158198-78-6(TFA Salt))
- Coclaurine Impurity 111 (CAS 2158201-34-2(TFA Salt))
- (+)-Coclaurine (CAS 2196-60-3)
Recommended Standards
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- Insulin Glargine (CAS 160337-95-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com