Chlorzoxazone Impurity 6 CAS CATO-C4X-27776
| CAS No. | CATO-C4X-27776 |
| Molecular Formula | C14H6Cl2N2O4 |
| Molecular Weight | 337.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Chlorzoxazone Impurity 6 (CAS CATO-C4X-27776), a pharmacopoeial impurity reference standard (molecular formula C14H6Cl2N2O4, MW 337.11 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Chlorzoxazone Impurity 6 (C14H6Cl2N2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Chlorzoxazone Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H6Cl2N2O4 |
| Molecular Weight | 337.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorzoxazone Standards
- Chlorzoxazone Impurity 3 (CAS CATO-C4X-27773)
- Chlorzoxazone Impurity 5 (CAS CATO-C4X-27775)
- Chlorzoxazone Impurity 4 (CAS CATO-C4X-27774)
- Chlorzoxazone Impurity N1 (CAS 57718-28-2)
- Chlorzoxazone-2-<SUP>13</SUP>C-3-<SUP>15</SUP>N-Hydroxy-<SUP>18</SUP>O (CAS 1173023-63-6)
- Chlorzoxazone-d3 (CAS 1185173-60-7)
- Chlorzoxazone (CAS 95-25-0)
- Chlorzoxazone USP Related Compound A (CAS 95-85-2)
Recommended Standards
- Benzenaminium, 3-carboxy-4-iodyl-N,N,N-trimethyl-, inner salt(AIBX) (CAS 2643968-51-6)
- 3-(Benzoyloxy)-5-bromo-2-hydroxybenzoic acid (CAS 107207-15-8)
- 2-Iodo-7-nitro-9H-fluorene (CAS 23055-47-2)
- (3E)-5-bromo-3-[(2,4-difluorophenyl)imino]-2,3-dihydro-1H-indol-2-one 118416-28-7 MS-8800 (CAS 118416-28-7)
- Sitafloxacin Impurity 2 HCl (CAS CATO-C4X-11552)
- Ilaprazole Impurity 49（碘盐C4X-1130124更便宜） (CAS CATO-C4X-113049)
- Fasudil Impurity 16 (CAS 1263357-67-0)
- N,N'-(Ethane-1,2-diylidene)bis(2,4,6-trimethylaniline) (CAS 56222-36-7)
- 4-(Dimethylamino)-8-methoxy-2-methylquinoline-6-carbaldehyde (CAS 89446-17-3)
- exo-8-Boc-8-azabicyclo[3.2.1]octan-2-amine (CAS 1408074-65-6)
- 4-Chloro-7-(2-methoxyethoxy)quinazolin-6-ol (CAS 1145671-43-7)
- Thiophen-2(3H)-one (CAS 20893-64-5)
- 2-(chloromethyl)oxetane (CAS 45377-87-5)
- Semaglutide (CAS CATO-C4X-2226105)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com