Peficitinib Impurity 30 CAS CATO-C4X-280730
| CAS No. | CATO-C4X-280730 |
| Molecular Formula | C18H20ClN3O2 |
| Molecular Weight | 345.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 345.82 g/mol gives Peficitinib Impurity 30 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Peficitinib Impurity 30 (CAS CATO-C4X-280730), a pharmacopoeial impurity reference standard (molecular formula C18H20ClN3O2, MW 345.82 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Peficitinib Impurity 30 (C18H20ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Peficitinib Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20ClN3O2 |
| Molecular Weight | 345.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Peficitinib Standards
- Peficitinib Impurity 27 (CAS CATO-C4X-280727)
- Peficitinib N-Oxide Impurity 19 (CAS CATO-C4X-280719)
- Peficitinib Impurity 1 (CAS 2055576-51-5)
- Peficitinib Impurity 5【Discontinued,See C4X-28071】 (CAS CATO-C4X-28075)
- Peficitinib Impurity 26 (CAS 944116-87-4)
- Peficitinib Impurity 31 (CAS CATO-C4X-280731)
- Peficitinib Impurity 9 (CAS 944123-15-3)
- Peficitinib Impurity 12 (CAS 944118-02-9)
Recommended Standards
- Atogepant Impurity 3 (CAS 1455358-11-8)
- N-[2-(4-Chlorophenoxy)phenyl]-4-methyl-1-piperazinecarboxamide (CAS 69478-73-5)
- Atogepant Impurity 77 (CAS CATO-C4X-328577)
- N-(4-Chlorophenyl)-2,3-dimethyl-6-phenyl-1,2,5-oxadiazinane-5-carboxamide (CAS 338794-83-5)
- Rufinamide Impurity 3 (CAS 106308-41-2)
- Hyoscine Butylbromide EP Impurity E (CAS 14861-14-4)
- Rimegepant Impurity 145 (CAS CATO-C4X-2487145)
- 2-(Pyridin-3-yl)benzonitrile (CAS 855196-53-1)
- 4-Ethyl-2-(isoxazol-5-yl)phenol (CAS 288401-58-1)
- 2-((4-Fluorobenzyl)thio)ethan-1-ol (CAS 203303-04-2)
- 3',3'',5',5''-Tetrabromophenolphthalein ethyl ester, indicator (CAS 1176-74-5)
- 5,8-Diethyl-7-hydroxy-6-dodecanone (CAS 31814-59-2)
- 2-oxo-1H,2H,3H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 1190313-69-9)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
Why CATO?
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