Sacubitril impurity 51 CAS CATO-C4X-280951
| CAS No. | CATO-C4X-280951 |
| Molecular Formula | C44H52N2O6 |
| Molecular Weight | 704.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Sacubitril impurity 51 (CAS CATO-C4X-280951), a pharmacopoeial impurity reference standard (molecular formula C44H52N2O6, MW 704.89 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Sacubitril impurity 51 (C44H52N2O6) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sacubitril impurity 51 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C44H52N2O6 |
| Molecular Weight | 704.89 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Sacubitril Standards
- Sacubitril Impurity 39 (CAS CATO-C4X-280939)
- Sacubitril Impurity 35 (CAS CATO-C4X-280935)
- Sacubitril Impurity 34 (CAS CATO-C4X-280934)
- Sacubitril Impurity 33 (CAS CATO-C4X-280933)
- Sacubitril Impurity 24 (CAS 2459446-52-5)
- Sacubitril Impurity 22 (CAS 2459446-53-6)
- Sacubitril impurity 47 (CAS CATO-C4X-280947)
- Sacubitril Impurity 29 (CAS CATO-C4X-280929)
Recommended Standards
- Fmoc-Arg(t-Bu,Pbf)-OH (CAS 1060769-44-9)
- Voacamine (CAS 3371-85-5)
- Raloxifene EP Impurity A (CAS 1159977-58-8)
- 12-(Bis(4-methoxyphenyl)(phenyl)methoxy)dodecyl (2-cyanoethyl) diisopropylphosphoramidite (CAS 158665-27-1)
- Olaparib Impurity 128 (CAS CATO-C4X-1135128)
- Fluphenazine Impurity 11 (CAS CATO-C4X-123111)
- Ticagrelor Impurity 112 (CAS CATO-C4X-1093112)
- 5-Amino-1-(2-(methylsulfonyl)ethyl)pyridin-2(1h)-one (CAS 1178695-22-1)
- 6-Bromo-5-methyl-2,3-dihydro-1H-inden-1-one (CAS 1147548-82-0)
- 6-Chloro-2-fluoro-3-methylbenzamide (CAS 286474-61-1)
- 3-Methyl-N-(4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)benzofuran-2-carboxamide (CAS 876720-96-6)
- 4-Chloro-3-thiomorpholinomethyl benzophenone (CAS 898763-05-8)
- N-(3-Hydroxybutyl)-4-piperidinecarboxamidehydrochloride (CAS 1220019-10-2)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com