Alectinib Impurity 92 CAS CATO-C4X-283692
| CAS No. | CATO-C4X-283692 |
| Molecular Formula | C12H14I2O2 |
| Molecular Weight | 444.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C12H14I2O2, Alectinib Impurity 92 contains a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 444.05 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Alectinib Impurity 92 (CAS CATO-C4X-283692, C12H14I2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14I2O2 |
| Molecular Weight | 444.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
Related Alectinib Standards
- Alectinib Impurity 6 (CAS 1256584-80-1)
- Alectinib Impurity 56 (CAS CATO-C4X-283656)
- Alectinib Impurity 15 (CAS 1256584-81-2)
- Alectinib Impurity 7 (CAS 1256585-04-2)
- Alectinib impurity 03 (CAS 1820882-01-6)
- Alectinib Impurity 43 (CAS CATO-C4X-283643)
- Alectinib Impurity 10 (CAS 1256584-74-3)
- Alectinib Impurity 49 (CAS CATO-C4X-283649)
Recommended Standards
- Trichlorodocosylsilane (CAS 7325-84-0)
- 3-(4-Bromophenyl)-N-(4-iodophenyl)-3-oxopropanamide (CAS 1148041-59-1)
- (E)-3-(4-ethoxy-3,5-diiodophenyl)acrylic acid (CAS 938018-89-4)
- 1,1,1,3,3,5,5,7,7,9,9,11,11-Tridecafluoro-2,4,6,8,10-pentaoxadodecan-12-oic acid (CAS 39492-91-6)
- Clofazimine Impurity 22 (CAS CATO-C4X-207122)
- CAS 31264-06-9 (CAS 31264-06-9)
- Dyclonine Impurity 22 (CAS CATO-C4X-188122)
- 1-(tert-Butyl) 3-ethyl 5,5-dimethyl-4-oxopiperidine-1,3-dicarboxylate (CAS 1956365-47-1)
- (3-(Piperidin-1-ylmethyl)phenyl)boronic acid hydrochloride (CAS 1072946-21-4)
- 2-(2,5-Difluorophenyl)-2-(methylamino)acetic acid (CAS 1192660-36-8)
- Zuranolone impurity 2 (CAS CATO-C4X-30382)
- 1,3-Diphenyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (CAS 24086-34-8)
- 1H-Imidazole-4,5-dicarboxylic acid, 1-phenyl-, hydrochloride (1:1) (CAS 2007915-70-8)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com