Nefopam Impurity 33 CAS CATO-C4X-283733
| CAS No. | CATO-C4X-283733 |
| Molecular Formula | C17H18BrNO2 |
| Molecular Weight | 348.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Nefopam Impurity 33 (CAS CATO-C4X-283733), a pharmacopoeial impurity reference standard (molecular formula C17H18BrNO2, MW 348.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Nefopam Impurity 33 (C17H18BrNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 348.23 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C17H18BrNO2 |
| Molecular Weight | 348.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Nefopam Standards
- Nefopam Impurity 31 (CAS CATO-C4X-283731)
- Nefopam Impurity 32 (CAS CATO-C4X-283732)
- Nefopam impurity 15 (CAS CATO-C4X-283715)
- Nefopam Impurity 6 (CAS 69984-25-4)
- Nefopam impurity 17 (CAS 82561-25-9)
- Nefopam impurity 16 (CAS CATO-C4X-283716)
- Nefopam Impurity 21 (CAS CATO-C4X-283721)
- Nefopam Impurity 4 (CAS 24833-47-4)
Recommended Standards
- Tert-butyl methyl(3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate (CAS 1032758-82-9)
- Tert-butyl ethyl(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate (CAS 1032758-86-3)
- N-(4-Bromophenyl)-4-(o-tolyloxy)butanamide (CAS 385373-45-5)
- (4-Benzylpiperazin-1-yl)(4-bromo-1h-pyrrol-2-yl)methanone (CAS 1060944-10-6)
- Relugolix Impurity 198 (CAS CATO-C4X-2429198)
- Tolvaptan Impurity 15 (CAS 1346599-56-1)
- Tofacitinib Impurity 245 (CAS CATO-C4X-1079245)
- 1-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)propan-2-amine (CAS 948007-33-8)
- (R)-2-acetamido-3-(3-hydroxyphenyl)propanoic acid (CAS 1610380-88-5)
- 1-(2-Methylphenyl)-1H-pyrazole (CAS 20157-44-2)
- 2-Butenedioic acid (2E)-, polymer with 1,3-butadiene, ethenylbenzene and methyl 2-methyl-2-propenoate (CAS 53832-00-1)
- 1-(2-(2H-Benzo[d][1,2,3]triazol-2-yl)ethyl)-1H-benzo[d][1,2,3]triazole (CAS 116477-11-3)
- 4-Benzhydryl-N-butylpiperazine-1-carboxamide (CAS 681801-59-2)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
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