Vericiguat Impurity 35 CAS CATO-C4X-289635
| CAS No. | CATO-C4X-289635 |
| Molecular Formula | C19H16F2N8O3 |
| Molecular Weight | 442.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 442.38 g/mol gives Vericiguat Impurity 35 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Vericiguat Impurity 35 (CAS CATO-C4X-289635, C19H16F2N8O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H16F2N8O3, Vericiguat Impurity 35 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 442.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16F2N8O3 |
| Molecular Weight | 442.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Vericiguat Standards
- Vericiguat Impurity 21 (CAS CATO-C4X-289621)
- Vericiguat impurity 49 (CAS CATO-C4X-289649)
- Vericiguat Impurity 12 (CAS CATO-C4X-289612)
- Vericiguat Impurity 18 (CAS CATO-C4X-289618)
- Vericiguat impurity 48 (CAS CATO-C4X-289648)
- Vericiguat impurity 54 (CAS CATO-C4X-289654)
- Vericiguat Impurity 78 (CAS CATO-C4X-289678)
- Vericiguat Impurity 36 (CAS CATO-C4X-289636)
Recommended Standards
- N-Nitroso-N-Desmethyl Cariprazine (CAS CATO-C4X-24086)
- (S)-N-[2-[7-Allyl-5-bromo-6-benzyloxy-2,3-dihydro-1H-inden-1-yl]ethyl]propanamide (CAS 1246820-29-0)
- Vilanterol Impurity 72 (CAS CATO-C4X-193572)
- N-(2-Cyanophenyl)-4-{3-[6-(trifluoromethyl)-3-pyridinyl]-1,2,4-oxadiazol-5-yl}-1-piperidinecarboxamide (CAS 909677-17-4)
- Pretomanid Impurity 16 (CAS CATO-C4X-260616)
- Relebactam Impurity 87 (CAS 2540656-36-6)
- Nintedanib impurity 108 (CAS CATO-C4X-1814108)
- 2'-Deoxy-7-carbaisoguanosine (CAS 103173-80-4)
- 5-Ethyl-1-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1094440-61-5)
- 3-(n-Benzylmethanesulfonamido)propanoic acid (CAS 340025-20-9)
- 5-(Thiophen-2-yl)-1,2,4-oxadiazol-3-amine (CAS 73631-19-3)
- 3-Hydroxy-N-desethyl-N-benzyl Lidocaine (CAS 1797131-04-4)
- Quinoxaline-5-carbonyl chloride (CAS 717871-86-8)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788692)
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