Vericiguat Impurity 18 CAS CATO-C4X-289618
| CAS No. | CATO-C4X-289618 |
| Molecular Formula | C20H18F2N8O2 |
| Molecular Weight | 440.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Vericiguat Impurity 18.
Vericiguat Impurity 18 (CAS CATO-C4X-289618) is a certified pharmaceutical impurity reference standard with the molecular formula C20H18F2N8O2 and a molecular weight of 440.41 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Vericiguat Impurity 18 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 440.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Vericiguat Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H18F2N8O2 |
| Molecular Weight | 440.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Vericiguat Standards
- Vericiguat Impurity 12 (CAS CATO-C4X-289612)
- Vericiguat impurity 48 (CAS CATO-C4X-289648)
- Vericiguat Impurity 78 (CAS CATO-C4X-289678)
- Vericiguat Impurity 21 (CAS CATO-C4X-289621)
- Vericiguat Impurity 35 (CAS CATO-C4X-289635)
- Vericiguat impurity 49 (CAS CATO-C4X-289649)
- Vericiguat impurity 54 (CAS CATO-C4X-289654)
- Vericiguat Impurity 36 (CAS CATO-C4X-289636)
Recommended Standards
- Folic Acid Impurity 53 (CAS CATO-C4X-139553)
- 2-((4-Methoxyphenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide (CAS 1092829-79-2)
- Methotrexate EP Impurity B (CAS 54-62-6)
- Cortisone Phosphate (CAS 508-95-2)
- Lubiprostone Impurity 31 (CAS CATO-C4X-113631)
- Belumosudil Impurity 59 (CAS CATO-C4X-298859)
- Propofol EP Impurity A (CAS 2934-05-6)
- 4-(Pyridin-3-yl)pyrimidine (CAS 98589-71-0)
- BENZYL ETHYL(TETRAHYDRO-2H-PYRAN-4-YL)CARBAMATE (CAS 1823231-98-6)
- 1-Benzoylanthracene-9,10-dione (CAS 61726-79-2)
- Methyl 3-(1,6-dihydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-3-yl)propanoate (CAS 1196475-33-8)
- (2S)-2-Amino-2,3-dimethyl-butanenitrile D-(-)-Tartaric Acid (CAS 952577-53-6)
- 4-Chloro-N-2-propen-1-yl-3-(trifluoromethyl)benzenesulfonamide (CAS 730986-30-8)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com