Vericiguat Impurity 70 CAS CATO-C4X-289670
| CAS No. | CATO-C4X-289670 |
| Molecular Formula | C20H14F2N8O3 |
| Molecular Weight | 452.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Vericiguat Impurity 70 (C20H14F2N8O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Vericiguat Impurity 70 (CAS CATO-C4X-289670), a pharmacopoeial impurity reference standard (molecular formula C20H14F2N8O3, MW 452.37 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vericiguat Impurity 70 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H14F2N8O3 |
| Molecular Weight | 452.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Vericiguat Standards
- Vericiguat Impurity 36 (CAS CATO-C4X-289636)
- Vericiguat Impurity 94 (CAS CATO-C4X-289694)
- Vericiguat Impurity 13 (CAS CATO-C4X-289613)
- Vericiguat Impurity 66 (CAS CATO-C4X-289666)
- Vericiguat Impurity 58 (CAS CATO-C4X-289658)
- Vericiguat Impurity 11 (CAS 1350653-29-0)
- Vericiguat Impurity 23 (CAS CATO-C4X-289623)
- Vericiguat Impurity 28 (CAS CATO-C4X-289628)
Recommended Standards
- N-(4-(4-(Bis(2-chloroethyl)amino)phenoxy)phenyl)quinolin-4-amine (CAS 133331-86-9)
- 2-Chloro-N-{4-[(2-chlorophenyl)sulfanyl]phenyl}-4-methanesulfonylbenzamide (CAS 339105-60-1)
- 4-((1-Carboxypentyl)oxy)-2-hydroxy-5-((2-(trifluoromethoxy)phenyl)ethynyl)benzoic acid (CAS 1772609-48-9)
- N-Acetyl Sitagliptin-d3 (CAS 1795785-80-6)
- Ivabradine impurity 74 (CAS CATO-C4X-111974)
- Alprazolam EP Impurity F (CAS 37945-07-6)
- Acetylcysteine Impurity 10 HCl (CAS 907565-13-3(Free Acid))
- (3-Methyl-5-(trifluoromethoxy)phenyl)methanamine (CAS 916420-60-5)
- N1,N4,2,5-Tetrahydroxyterephthalamide (CAS 2243978-33-6)
- (3-(Isopentyloxy)-4-methoxyphenyl)(methyl)sulfane (CAS 1443303-28-3)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-sulfamoylphenethyl)acetamide (CAS 478063-71-7)
- 1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate (CAS 338760-26-2)
- 2-{[(tert-butoxy)carbonyl]amino}-3-(1H-pyrrol-2-yl)propanoic acid (CAS 1379870-15-1)
- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
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