Entrectinib Impurity 3 CAS CATO-C4X-29053

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-29053
Molecular FormulaC48H60FN11O4
Molecular Weight874.06 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Entrectinib Impurity 3 CAS CATO-C4X-29053 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 874.06 g/mol gives Entrectinib Impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Entrectinib Impurity 3 (CAS CATO-C4X-29053) is a certified pharmaceutical impurity reference standard with the molecular formula C48H60FN11O4 and a molecular weight of 874.06 g/mol.

Based on its molecular formula C48H60FN11O4, Entrectinib Impurity 3 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 874.06 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Entrectinib Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC48H60FN11O4
Molecular Weight874.06 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)24.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing
Nitrogen Atoms11

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