Resmetirom impurity 116 CAS CATO-C4X-2912116
| CAS No. | CATO-C4X-2912116 |
| Molecular Formula | C32H28Cl4N8O7 |
| Molecular Weight | 778.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Resmetirom impurity 116 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 778.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Resmetirom impurity 116 (CAS CATO-C4X-2912116), a pharmacopoeial impurity reference standard (molecular formula C32H28Cl4N8O7, MW 778.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Resmetirom impurity 116 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C32H28Cl4N8O7 |
| Molecular Weight | 778.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Resmetirom Standards
- Resmetirom impurity 117 (CAS CATO-C4X-2912117)
- Resmetirom impurity 111 (CAS CATO-C4X-2912111)
- Resmetirom impurity 105 (CAS CATO-C4X-2912105)
- Resmetirom Impurity 11 (CAS CATO-C4X-291211)
- Resmetirom impurity 88 (CAS CATO-C4X-291288)
- Resmetirom Impurity 97 (CAS CATO-C4X-291297)
- Resmetirom impurity 119 (CAS CATO-C4X-2912119)
- Resmetirom impurity 106 (CAS CATO-C4X-2912106)
Recommended Standards
- 1,1'-Dihexadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate, 90% (CAS 78566-75-3)
- Di-Fmoc-seleno-L-cystine (CAS 1639843-33-6)
- Methylperfluoropentadecanoate (CAS 203303-00-8)
- 2-(3-(tert-Butyl)-4-hydroxyphenoxy)-N-(4-chloro-3-((5-oxo-1-(2,4,6-trichloro-phenl)-4,5-dihydro-1H-pyrazol-3-yl)amino)phenyl)tetradecanamide (CAS 61354-99-2)
- Ibrutinib Impurity 132 (CAS CATO-C4X-1064132)
- Finasteride Impurity 45 (CAS CATO-C4X-164545)
- Aztreonam Impurity 45 (CAS CATO-C4X-152245)
- 4-(Tert-butyl)-N-((6-nitrobenzo[d][1,3]dioxol-5-yl)methyl)aniline (CAS 306730-49-4)
- 4-(Methylamino)piperidine-4-carboxylic acid (CAS 790616-58-9)
- [3-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)propyl]amine dihydrochloride (CAS 93808-11-8)
- 5-O-DMT-uridine (CAS 81246-79-9)
- N-((5-bromopyridin-3-yl)methyl)-2-methylpropan-2-amine (CAS 1182425-71-3)
- Benzyl 2-(4-amino-2-oxopyrimidin-1(2H)-yl)acetate (CAS 211321-08-3)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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