Resmetirom impurity 105 CAS CATO-C4X-2912105
| CAS No. | CATO-C4X-2912105 |
| Molecular Formula | C26H22Cl6N6O2 |
| Molecular Weight | 663.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Resmetirom impurity 105 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Resmetirom impurity 105 (CAS CATO-C4X-2912105, C26H22Cl6N6O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Resmetirom impurity 105 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 663.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C26H22Cl6N6O2 |
| Molecular Weight | 663.21 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Resmetirom Standards
- Resmetirom Impurity 11 (CAS CATO-C4X-291211)
- Resmetirom impurity 88 (CAS CATO-C4X-291288)
- Resmetirom Impurity 97 (CAS CATO-C4X-291297)
- Resmetirom impurity 119 (CAS CATO-C4X-2912119)
- Resmetirom impurity 106 (CAS CATO-C4X-2912106)
- Resmetirom impurity 107 (CAS CATO-C4X-2912107)
- Resmetirom impurity 123 (CAS CATO-C4X-2912123)
- Resmetirom impurity 118 (CAS CATO-C4X-2912118)
Recommended Standards
- Allisartan Isoproxil Impurity N1 (CAS 120568-18-5)
- Allisartan Isoproxil Impurity 9 (CAS CATO-C4X-32179)
- 2-Chloro-5-[(2S,3S,4R,5R,6R)-3,4,5-tribenzyloxy-6-(benzyloxymethyl)tetrahydropyran-2-yl]benzaldehyde (CAS 842133-82-8)
- Broflanilide (CAS 1207727-04-5)
- Palonosetron Impurity 42 (CAS 2216755-70-1(free base))
- Empagliflozin Impurity 64 (CAS CATO-C4X-106564)
- Acetazolamide EP Impurity A (CAS 60320-32-3)
- Ethyl 2,4,6-trichloropyrimidine-5-carboxylate (CAS 87848-14-4)
- tert-Butyl (6-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)carbamate (CAS 1781357-63-8)
- [3-(Aminomethyl)phenyl]acetic acid hydrochloride (CAS 42288-55-1)
- (1-Methyl-1h-pyrrolo[2,3-b]pyridin-3-yl)methanamine (CAS 1092309-87-9)
- (4-(Aminomethyl)piperidin-1-yl)(2-chloropyridin-3-yl)methanone (CAS 187543-73-3)
- Adamantane-1,3,5,7-tetracarboxylic acid (CAS 100884-80-8)
- Palmitoyl Tripeptide -5 · 2 TFA (CAS 623172-56-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com