Letermovir Impurity 14 CAS CATO-C4X-291514
| CAS No. | CATO-C4X-291514 |
| Molecular Formula | C15H10F2N2O |
| Molecular Weight | 272.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Letermovir Impurity 14.
As a process- or degradation-related impurity, Letermovir Impurity 14 (CAS CATO-C4X-291514, C15H10F2N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C15H10F2N2O, Letermovir Impurity 14 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 272.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Letermovir Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10F2N2O |
| Molecular Weight | 272.25 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Letermovir Standards
- Letermovir Impurity 76 (CAS CATO-C4X-291576)
- Letermovir Impurity 133 (CAS CATO-C4X-2915133)
- Letermovir Impurity 13 (CAS CATO-C4X-291513)
- Letermovir Impurity 126 (CAS 884340-24-3)
- Letermovir Impurity 15 (CAS CATO-C4X-291515)
- Letermovir Impurity 51 (CAS CATO-C4X-291551)
- Letermovir Impurity 135 (CAS CATO-C4X-2915135)
- Letermovir Impurity 134 (CAS CATO-C4X-2915134)
Recommended Standards
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