Letermovir Impurity 134 CAS CATO-C4X-2915134
| CAS No. | CATO-C4X-2915134 |
| Molecular Formula | C11H17ClN2O |
| Molecular Weight | 228.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Letermovir Impurity 134 (CAS CATO-C4X-2915134) is a certified pharmaceutical impurity reference standard with the molecular formula C11H17ClN2O and a molecular weight of 228.72 g/mol.
The molecular framework of Letermovir Impurity 134 (C11H17ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H17ClN2O |
| Molecular Weight | 228.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Letermovir Standards
- Letermovir Impurity 102 (CAS CATO-C4X-2915102)
- Letermovir Impurity 73 (CAS CATO-C4X-291573)
- Letermovir Impurity 80 (CAS CATO-C4X-291580)
- Letermovir Impurity 97 (CAS CATO-C4X-291597)
- Letermovir Impurity 98 (CAS CATO-C4X-291598)
- Letermovir Impurity 14 (CAS CATO-C4X-291514)
- Letermovir Impurity 76 (CAS CATO-C4X-291576)
- Letermovir Impurity 133 (CAS CATO-C4X-2915133)
Recommended Standards
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- 5-Chloro-2-thiomorpholinoaniline (CAS 1042798-56-0)
- Lobeline impurity 18 (CAS CATO-C4X-181818)
- Lenacapavir Impurity 13 (CAS CATO-C4X-324813)
- Mirogabalin Impurity 45 HCl (CAS CATO-C4X-292445)
- 3,5-Difluoro-1,2-benzenediamine (CAS 2369-29-1)
- N,1-Dimethyl-1H-1,2,3-triazole-4-carboxamide (CAS 57362-85-3)
- 4-(4-Fluorophenyl)pyrrolidin-3-ol (CAS 1936182-09-0)
- 5-Chloro-1-(triisopropylsilyl)-6-((trimethylsilyl)ethynyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1305325-25-0)
- Carbetocin Impurity 12 (CAS CATO-C4X-191112)
- Fmoc-β-azido-D-Aib-OH · BHA (CAS 1926163-91-8)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
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