Letermovir Impurity 133 CAS CATO-C4X-2915133
| CAS No. | CATO-C4X-2915133 |
| Molecular Formula | C15H24ClN3O |
| Molecular Weight | 297.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Letermovir Impurity 133 (CAS CATO-C4X-2915133, C15H24ClN3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Letermovir Impurity 133 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 297.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Letermovir Impurity 133 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H24ClN3O |
| Molecular Weight | 297.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Letermovir Standards
- Letermovir Impurity 13 (CAS CATO-C4X-291513)
- Letermovir Impurity 126 (CAS 884340-24-3)
- Letermovir Impurity 15 (CAS CATO-C4X-291515)
- Letermovir Impurity 51 (CAS CATO-C4X-291551)
- Letermovir Impurity 135 (CAS CATO-C4X-2915135)
- Letermovir Impurity 76 (CAS CATO-C4X-291576)
- Letermovir Impurity 14 (CAS CATO-C4X-291514)
- Letermovir impurity 138 (CAS CATO-C4X-2915138)
Recommended Standards
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- Nickel antimonide (CAS 12503-49-0)
- Elacestrant impurity 8 (CAS 2477812-39-6)
- Dotinurad Impurity 85 (CAS 80547-63-3)
- Axitinib Impurity 15 (CAS CATO-C4X-107115)
- Magnesium acrylate (CAS 5698-98-6)
- Methoxyphenamine Impurity 72 (CAS 71828-08-5)
- Fmoc-4-methyl-DL-tryptophan (CAS 1219279-39-6)
- 3-{[(8-bromo-2,3-dihydro-1,4-benzodioxin-6-yl)methyl]amino}propanoic acid hydrochloride (CAS 1354949-74-8)
- 2-(Cycloheptylamino)-4-methylpentan-1-ol (CAS 1183738-42-2)
- n-(3-Bromophenyl)-4-methylthiazole-5-carboxamide (CAS 1016708-69-2)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
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