Letermovir Impurity 66 CAS CATO-C4X-291566
| CAS No. | CATO-C4X-291566 |
| Molecular Formula | C41H45F3N6O5 |
| Molecular Weight | 758.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Letermovir Impurity 66 (CAS CATO-C4X-291566, C41H45F3N6O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Letermovir Impurity 66 (C41H45F3N6O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Letermovir Impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C41H45F3N6O5 |
| Molecular Weight | 758.83 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Letermovir Standards
- Letermovir Impurity N3 (CAS CATO-CP155164)
- Letermovir Impurity 43 (CAS CATO-C4X-291543)
- Letermovir Impurity N5 (CAS CATO-CP155166)
- Letermovir Impurity 120 (CAS CATO-C4X-2915120)
- Letermovir impurity 118 (CAS 2758792-75-3)
- Letermovir impurity 119 (CAS 2864441-61-0)
- Letermovir Impurity 36 (CAS CATO-C4X-291536)
- Letermovir Impurity 32 (CAS 2994645-03-1)
Recommended Standards
- Olmesartan Impurity 111 (CAS 1073117-27-7)
- Jatrophane 2 (CAS 210108-86-4)
- Lurbinectedin Impurity 12 (CAS CATO-C4X-311412)
- Decaglycerol (CAS 9041-07-0)
- Rosuvastatin Impurity 96 (CAS 521974-00-5)
- Finerenone Impurity 15 (CAS 3046142-41-7)
- Rabeprazole EP Impurity B (CAS 117977-21-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com