Abemaciclib Impurity 28 CAS CATO-C4X-293728
| CAS No. | CATO-C4X-293728 |
| Molecular Formula | C18H22N6O2 |
| Molecular Weight | 354.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Abemaciclib Impurity 28 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 354.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Abemaciclib Impurity 28 (CAS CATO-C4X-293728), a pharmacopoeial impurity reference standard (molecular formula C18H22N6O2, MW 354.41 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Abemaciclib Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22N6O2 |
| Molecular Weight | 354.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Abemaciclib Standards
- Abemaciclib Impurity 170 (CAS CATO-C4X-2937170)
- Abemaciclib Impurity 125 (CAS CATO-C4X-2937125)
- Abemaciclib Impurity 126 (CAS CATO-C4X-2937126)
- Abemaciclib Impurity 163 (CAS CATO-C4X-2937163)
- Abemaciclib Impurity 129 (CAS CATO-C4X-2937129)
- Abemaciclib Impurity 55 (CAS 2379819-71-1)
- Abemaciclib Impurity 89 (CAS CATO-C4X-293789)
- Abemaciclib impurity 113 (CAS CATO-C4X-2937113)
Recommended Standards
- N-(4-(Pyridin-3-yl)thiazol-2-yl)-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-amine (CAS 862976-66-7)
- (H-Gly-Cys-OH)? (Disulfide bond) (CAS 26798-52-7)
- Ethyl (5-amino-3-((methyl(phenyl)amino)methyl)-1,2-dihydropyrido[3,4-b]pyrazin-7-yl)carbamate (CAS 80434-77-1)
- H-Ala-His-Lys-OH (CAS 126828-32-8)
- Apixaban Impurity 19 (CAS 503615-03-0)
- Bevantolol impurity 2 (CAS 204584-12-3)
- Meropenem Impurity 19 (CAS 90776-58-2)
- N-(tert-butoxycarbonyl)-S-(4-methylbenzyl)-D-homocysteine (CAS 214630-13-4)
- 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, polymer with 2-aminoethyl 2-methyl-2-propenoate hydrochloride and butyl 2-propenoate (CAS 110389-14-5)
- 4-Amino-1,2-dihydroxyanthracene-9,10-dione (CAS 2835-53-2)
- 2,3,4,6-Tetra-O-benzyl-D-galactopyranose (CAS 53081-25-7)
- Erythromycin E carbonate (CAS CATO-C4X-100162)
- 4-Methoxybenzyl (E)-styrylcarbamate (CAS 338413-37-9)
- Cyclolinopeptide B (CAS 193139-41-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com