Capmatinib Impurity 7 CAS CATO-C4X-29857
| CAS No. | CATO-C4X-29857 |
| Molecular Formula | C23H16ClFN6O |
| Molecular Weight | 446.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Capmatinib Impurity 7 (C23H16ClFN6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Capmatinib Impurity 7 (CAS CATO-C4X-29857, C23H16ClFN6O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Capmatinib Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H16ClFN6O |
| Molecular Weight | 446.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
Related Capmatinib Standards
- Capmatinib (CAS 1029712-80-8)
- Capmatinib Impurity 5 (CAS 1029714-88-2)
- Capmatinib M18 Metabolite (CAS 1029713-99-2)
- Capmatinib Impurity 6 (CAS CATO-C4X-29856)
- Capmatinib Impurity 3 (CAS CATO-C4X-29853)
- Capmatinib Impurity 9 (CAS CATO-C4X-29859)
- Capmatinib Impurity 4 (CAS 1243392-80-4)
- Capmatinib Dihydrochloride (CAS 1197376-85-4)
Recommended Standards
- 1-Methyl-2-(pentan-3-yl)quinolin-4(1H)-one (CAS 126365-17-1)
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- N-(5-Chloro-3-(phenylsulfonyl)-1H-indol-2-yl)-2,4-difluorobenzamide (CAS 918493-42-2)
- 5-(5-Chloro-2-methoxybenzenesulfonyl)-8-(trifluoromethyl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline (CAS 861207-45-6)
- Apalutamide Impurity 54 (CAS 1332389-57-7)
- Apremilast Impurity 114 (CAS CATO-C4X-1009114)
- Ruxolitinib Impurity 6 (CAS 1911644-32-0)
- PDTSTPD (CAS 1279109-93-1)
- (R)-2-(Cyclopropyl(1-methylpiperidin-3-yl)amino)ethanol (CAS 1353998-15-8)
- 2-Benzylcyclopropane-1-carboxylic acid, mixture of diastereomers (CAS 103986-55-6)
- Carbomer 934 (Technical Grade) (CAS 9007-16-3)
- 4-Benzoyl-1-[(2-chloro-6-fluorophenyl)methyl]-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317822-18-7)
- 5-fluoro-2-methyl-1,2,3,4-tetrahydronaphthalen-1-one (CAS 1368766-25-9)
- Smac-N7 Peptide (CAS 401913-57-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com