Belumosudil Impurity 57 CAS CATO-C4X-298857
| CAS No. | CATO-C4X-298857 |
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Belumosudil Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Belumosudil Impurity 57 (CAS CATO-C4X-298857, C12H15NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Belumosudil Impurity 57 (C12H15NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Belumosudil Standards
- Belumosudil Impurity 55 (CAS CATO-C4X-298855)
- Belumosudil Impurity 56 (CAS CATO-C4X-298856)
- Belumosudil Impurity 65 (CAS CATO-C4X-298865)
- Belumosudil Impurity 31 (CAS 954269-05-7)
- Belumosudil Impurity 32 (CAS 1208966-76-0)
- Belumosudil Impurity 30 (CAS CATO-C4X-298830)
- Belumosudil Impurity 34 (CAS 1789444-04-7)
- Belumosudil Impurity 64 (CAS CATO-C4X-298864)
Recommended Standards
- N-Lactoyl-Phenylalanine (CAS 183241-73-8)
- Ethopabate (CAS 59-06-3)
- Noscapine impurity 3 (CAS 82-54-2)
- Disperse Red 9 (CAS 82-38-2)
- Pregabalin Impurity 118 (CAS CATO-C4X-1312118)
- Ondansetron Impurity 12 (CAS 1365727-09-8)
- Abemaciclib impurity 121 (CAS CATO-C4X-2937121)
- Flomoxef Impurity 29 (CAS 2095697-75-7)
- 129768-50-9 2-{[Chloro(phenyl)acetyl]amino}benzamide MFCD13706330 (CAS 129768-50-9)
- Ethyl 5-(hydroxymethyl)-1-phenyl-1H-pyrazole-3-carboxylate (CAS 40753-66-0)
- 2-Methyl-1H-imidazo[1,2-b]pyrazole-1-carbaldehyde (CAS 135830-21-6)
- (S)-(-)-1-Phenylethylamine (CAS 2627-86-3)
- Ethyl 4-fluoro-1H-imidazole-5-carboxylate (CAS 33235-31-3)
- D-Phe22-Tirzepatide (CAS CATO-CPTD788912)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com