Phoxim Impurity 7 CAS CATO-C4X-29977
| CAS No. | CATO-C4X-29977 |
| Molecular Formula | C12H15N2O3PS |
| Molecular Weight | 298.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a phosphonate group, a hydroxyl group, an ether linkage, Phoxim Impurity 7 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 298.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Phoxim Impurity 7 (CAS CATO-C4X-29977, C12H15N2O3PS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15N2O3PS |
| Molecular Weight | 298.30 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Phoxim Standards
Recommended Standards
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- Pemetrexed Impurity 7 (CAS 137281-39-1)
- Ambroxol impurity 112 (CAS CATO-C4X-1085112)
- Faropenem Impurity 19 (CAS CATO-C4X-128919)
- Neostigmine EP Impurity C (CAS 16088-19-0)
- 2-(4-(Difluoromethyl)-2-hydroxy-5-iodopyridin-3-yl)acetonitrile (CAS 1807113-28-5)
- Chroman-8-amine (CAS 113722-25-1)
- tert-Butyl 8-benzyl-7-oxo-5-oxa-2,8-diazaspiro[3.5]nonane-2-carboxylate (CAS 1803594-77-5)
- 3-Amino-5-bromo-1-methyl-2,3-dihydro-1h-indol-2-one hydrochloride (CAS 1266685-37-3)
- 4-Azetidinomethyl-4-trifluoromethylbenzophenone (CAS 898756-86-0)
- 5-(4-Methoxyphenyl)-1,2,4-oxadiazol-3-amine (CAS 23275-52-7)
- Neuropeptide S (rat) (CAS 412938-75-1)
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