Oclacitinib impurity 6 CAS CATO-C4X-30186
| CAS No. | CATO-C4X-30186 |
| Molecular Formula | C28H32N4O5S2 |
| Molecular Weight | 568.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Oclacitinib impurity 6 (CAS CATO-C4X-30186, C28H32N4O5S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Oclacitinib impurity 6 (C28H32N4O5S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H32N4O5S2 |
| Molecular Weight | 568.71 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Oclacitinib Standards
- Oclacitinib Impurity 18 (CAS 1208319-32-7)
- Oclacitinib impurity 5 (CAS CATO-C4X-30185)
- Oclacitinib Impurity 20 (CAS 1312034-36-8)
- Oclacitinib Impurity 22 (CAS 1208319-34-9)
- Oclacitinib Impurity 31 (CAS CATO-C4X-301831)
- Oclacitinib Impurity 21 (CAS 1208319-28-1)
- Oclacitinib Impurity 32 (CAS CATO-C4X-301832)
- Oclacitinib Impurity 39 (CAS CATO-C4X-301839)
Recommended Standards
- Atrasentan Impurity 77 (CAS 1058551-16-8)
- Atrasentan Impurity 78 (CAS 1058551-22-6)
- Protoporphyrinogen IX (CAS 7412-77-3)
- (R)-2-Methoxy-3-(octadecyloxy)propyl ((1R,2R,3S,4R)-2,3,4-trihydroxycyclohexyl) hydrogen phosphate (CAS 701976-55-8)
- Amisulpride impurity 51 (CAS CATO-C4X-104551)
- Salmeterol EP Impurity C (CAS 94749-11-8)
- Acarbose EP Impurity E (CAS CATO-C4X-11735)
- tert-Butyl 5-cyano-3-iodo-1H-indole-1-carboxylate (CAS 864685-26-7)
- 3-[(4-bromo-2-fluorophenyl)amino]-2-methylpropanenitrile (CAS 1099685-65-0)
- tert-Butyl 3-(4-chlorophenyl)-3-hydroxyazetidine-1-carboxylate (CAS 1447464-04-1)
- [2-(2,4-difluorophenyl)propyl](methyl)amine (CAS 1368462-69-4)
- 3-(6-Methoxynaphthalen-2-yl)-1-phenyl-1h-pyrazole-4-carbaldehyde (CAS 957354-89-1)
- N-(2-Nitrophenyl)acridin-9-amine (CAS 80260-77-1)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
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