Hydroxychloroquine Impurity 74 CAS 2411340-32-2
| CAS No. | 2411340-32-2 |
| Molecular Formula | C27H30Cl2N4O |
| Molecular Weight | 497.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Hydroxychloroquine Impurity 74 (CAS 2411340-32-2) is a certified pharmaceutical impurity reference standard with the molecular formula C27H30Cl2N4O and a molecular weight of 497.46 g/mol.
Based on its molecular formula C27H30Cl2N4O, Hydroxychloroquine Impurity 74 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 497.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H30Cl2N4O |
| Molecular Weight | 497.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine Impurity 35 (CAS CATO-C4X-183535)
- Hydroxychloroquine Impurity 43 (CAS CATO-C4X-183543)
- Hydroxychloroquine Impurity 39 (CAS CATO-C4X-183539)
- Hydroxychloroquine impurity 82 (CAS CATO-C4X-183582)
- Hydroxychloroquine Impurity 37 (CAS CATO-C4X-183537)
- Hydroxychloroquine Impurity 44 (CAS CATO-C4X-183544)
- Hydroxychloroquine Impurity 41 (CAS CATO-C4X-183541)
- Hydroxychloroquine Impurity 42 (CAS CATO-C4X-183542)
Recommended Standards
- 2-(1-(4-Ethoxybenzoyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 1007998-55-1)
- Methotrexate impurity 51 (CAS CATO-C4X-115451)
- 4,4'-(2-(4-Bromophenyl)-2-phenylethene-1,1-diyl)bis(N,N-dimethylaniline) (CAS 1071547-23-3)
- 4-Nitro-Z-Gly-Trp-Gly-OH (M-1595.0050) (CAS 64792-79-6)
- Tolvaptan Impurity 39 (CAS 1711-06-4)
- Indapamide Impurity 51 (CAS CATO-C4X-140051)
- Estazolam Impurity 8 (CAS CATO-C4X-19228)
- 7-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline (CAS 2776103-53-6)
- 2-(4-Methylphenoxymethyl)-1,3-thiazole-4-carboxylic acid (CAS 875858-78-9)
- Mdl-860 (CAS 78940-62-2)
- 5-Nitro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (CAS 109793-85-3)
- 5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-amine 5711-61-5 5838AE C9H9N3O2 (CAS 5711-61-5)
- 2-Chloro-N-(3,4-dimethylphenyl)acetamide (CAS 2564-04-7)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com